The Spanish knew the bay and the island early; it was probably there that Cabeza de Vaca was shipwrecked in 1528. Settlement began in the 1830s. The natural port came gradually into its own despite scourges of yellow fever, hurricanes, and the occupation for a few months in 1862 by a small Union force. A 1900 hurricane resulted in thousands of deaths and left the city in ruins. Against future storms an enormous 10-mi (16-km)-long protective seawall was built; however, occasional hurricanes still cause much damage.
Of interest are the Texas Heroes monument, the Rosenberg Library, several old homes, and a 142-acre nature and entertainment complex that includes a 10-story glass pyramid with rain forests and a bamboo forest. A Coast Guard base and the Texas maritime academy are in Galveston, as is the Univ. of Texas Medical Branch, with a large group of hospitals, and a campus of Texas A&M Univ.
See E. Larson, Isaac's Storm (1999).