Collagen disease is a term previously used to describe
systemic autoimmune diseases (e.g.,
rheumatoid arthritis,
systemic lupus erythematosus, and
systemic sclerosis), but now is thought to be more appropriate for diseases associated with defects in
collagen, which is a component of the connective tissue.
The term "collagen disease" was coined by Dr. Paul Klemperer at Mount Sinai Hospital in New York City in 1941.
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