• Tse (Ц, ц), a letter of the Cyrillic alphabet
• Tse (surname) (謝), the Cantonese pronunciation of a Chinese surname
• Tirana Stock Exchange (TSE), the principal stock exchange in Albania.
• Tokyo Stock Exchange (TSE)
• Toronto Stock Exchange (TSX, formerly TSE)
• Torque Shader Engine (TSE)
• Transmissible spongiform encephalopathy (TSE) diseases
• Test of Spoken English, a test by Educational Testing Service
• Terminal Server Edition or Terminal Services (TSE)
• The Spirit Engine, a freeware computer game

See also

• Tsetse fly
• Taylor Series Expansion