space biology: see exobiology.

molecular biology, scientific study of the molecular basis of life processes, including cellular respiration, excretion, and reproduction. The term molecular biology was coined in 1938 by Warren Weaver, then director of the natural sciences program at the Rockefeller Foundation. In 1950 W. T. Astbury of the Univ. of Leeds used the term in its now accepted sense, to describe the area of research, closely related to and often overlapping biochemistry, conducted by biologists whose approach to and interest in biology are principally at the molecular level of organization. The field of molecular biology has grown with the increasing sophistication of available techniques and has quickly built upon its own increases in the understanding of biological processes. In the 1930s, with the help of the technique of ultracentrifugation, the macromolecules were first studied in detail and their crystalline properties described. In the 1940s the process by which individual genes produce their unique products began to be understood as resulting from the different sequences of the base pairs that make up the genes. In the 1950s Linus Pauling described the three-dimensional structure of proteins, and James Watson and Francis Crick described the double helix of the DNA molecule. Further advances were made in understanding DNA, protein, and virus synthesis and the regulation of genes, and by the 1970s, the techniques of genetic engineering were enabling molecular biologists to study higher plants and animals, opening up the possibility of manipulating plant and animal genes to achieve greater agricultural productivity. Such techniques also opened the way for the development of gene therapy.

marine biology, study of ocean plants and animals and their ecological relationships. Marine organisms may be classified (according to their mode of life) as nektonic, planktonic, or benthic. Nektonic animals are those that swim and migrate freely, e.g., adult fishes, whales, and squid. Planktonic organisms, usually very small or microscopic, have little or no power of locomotion and merely drift or float in the water. Benthic organisms live on the sea bottom and include sessile forms (e.g., sponges, oysters, and corals), creeping organisms (e.g., crabs and snails), and burrowing animals (e.g., many clams and worms). Seafloor areas called hydrothermal vents, with giant tube worms and many other unusual life forms, have been intensively studied by marine biologists in recent years.

The distribution of marine organisms depends on the chemical and physical properties of seawater (temperature, salinity, and dissolved nutrients), on ocean currents (which carry oxygen to subsurface waters and disperse nutrients, wastes, spores, eggs, larvae, and plankton), and on penetration of light. Photosynthetic organisms (plants, algae, and cyanobacteria), the primary sources of food, exist only in the photic, or euphotic, zone (to a depth of about 300 ft/90 m), where light is sufficient for photosynthesis. Since only about 2% of the ocean floor lies in the photic zone, photosynthetic organisms in the benthos are far less abundant than photosynthetic plankton (phytoplankton), which is distributed near the surface oceanwide. Very abundant phytoplankton include the diatoms and dinoflagellates (see Dinoflagellata). Heterotrophic plankton (zooplankton) include such protozoans as the foraminiferans; they are found at all depths but are more numerous near the surface. Bacteria are abundant in upper waters and in bottom deposits.

The scientific study of marine biology dates from the early 19th cent. and now includes laboratory study of organisms for their usefulness to humans and the effects of human activity on marine environments. Important marine biological laboratories include those at Naples, Italy; at Plymouth and Millport in England; and at Woods Hole, Mass., La Jolla, Calif., and Coral Gables, Fla. Research has been furthered by unmanned and manned craft, such as the submersible Alvin.

See also oceanography.

biology, the science that deals with living things. It is broadly divided into zoology, the study of animal life, and botany, the study of plant life. Subdivisions of each of these sciences include cytology (the study of cells), histology (the study of tissues), anatomy or morphology, physiology, and embryology (the study of the embryonic development of an individual animal or plant). Also included in biological studies are the sciences of genetics, evolution, paleontology, and taxonomy or systematics, the study of classification. The methods and attitudes of other sciences are brought to the study of biology in such fields as biochemistry (physiological chemistry), biophysics (the physics of life processes), bioclimatology and biogeography (ecology), bioengineering (the design of artificial organs), biometry or biostatistics, bioenergetics, and biomathematics. Evidences of early human observations of nature are seen in prehistoric cave art. Biological concepts began to develop among the early Greeks. The biological works of Aristotle include his observations and classification of his large collections of animals. The invention of the microscope in the 16th cent. gave a great stimulus to biology, broadening and deepening its scope and creating the sciences of microbiology, the study of microscopic forms of life, and microscopy, the microscopic study of living cells. Among the many who contributed to the science are Claude Bernard, Cuvier, Darwin, T. H. Huxley, Lamarck, Linnaeus, Mendel, and Pasteur. See marine biology.

Field of science concerned with the chemical structures and processes of biological phenomena at the molecular level. Having developed out of the related fields of biochemistry, genetics, and biophysics, the discipline is particularly concerned with the study of proteins, nucleic acids, and enzymes. In the early 1950s, growing knowledge of the structure of proteins enabled the structure of DNA to be described. The discovery in the 1970s of certain types of enzymes that can cut and recombine segments of DNA (see recombination) in the chromosomes of certain bacteria made recombinant-DNA technology possible. Molecular biologists use that technology to isolate and modify specific genes (see genetic engineering).

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Science that deals with the animals and plants of the sea and estuaries and with airborne and terrestrial organisms that depend directly on bodies of saltwater for food and other necessities. Marine biologists study the relations between ocean phenomena and the distribution and adaptations of organisms. Of particular interest are adaptations to the chemical and physical properties of seawater, the movements and currents of the ocean, the availability of light at various depths, and the composition of the sea floor. Other important areas of study are marine food chains, the distribution of economically important fish and crustaceans, and the effects of pollution. In the later 19th century, the emphasis was on collecting and cataloging marine organisms, for which special nets, dredges, and trawls were developed. In the 20th century, improved diving equipment, submersible craft, and underwater cameras and television have made direct observation possible.

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Study of the relationships between organisms and their environment. Physiological ecology focuses on the relationships between individual organisms and the physical and chemical features of their environment. Behavioral ecologists study the behaviours of individual organisms as they react to their environment. Population ecology is the study of processes that affect the distribution and abundance of animal and plant populations. Community ecology studies how communities of plant and animal populations function and are organized; it frequently concentrates on particular subsets of organisms such as plant communities or insect communities. Ecosystem ecology examines large-scale ecological issues, ones that often are framed in terms of measures such as biomass, energy flow, and nutrient cycling. Applied ecology applies ecological principles to the management of populations of crops and animals. Theoretical ecologists provide simulations of particular practical problems and develop models of general ecological relevance. Seealso systems ecology.

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Study of cells. Its earliest phase began with Robert Hooke's microscopic investigations of cork in 1665, during which he introduced the term cell to describe dead cork cells. Mathias Jacob Schleiden (in 1838) and Theodor Schwann (1839) were among the first to state clearly that cells are the fundamental units of both plants and animals. This pronouncement (the cell theory) was confirmed and elaborated by a series of discoveries and interpretations. In 1892 Oscar Hertwig (1849–1922) suggested that processes at the organism's level are reflections of cellular processes, thus establishing cytology as a separate branch of biology. Seealso physiology.

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Study of living things and their vital processes. An extremely broad subject, biology is divided into branches. The current approach is based on the levels of biological organization involved (e.g., molecules, cells, individuals, populations) and on the specific topic under investigation (e.g., structure and function, growth and development). According to this scheme, biology's main subdivisions include morphology, physiology, taxonomy, embryology, genetics, and ecology, each of which can be further subdivided. Alternatively, biology can be divided into fields especially concerned with one type of living thing; for example, botany (plants), zoology (animals), ornithology (birds), entomology (insects), mycology (fungi), microbiology (microorganisms), and bacteriology (bacteria). Seealso biochemistry; molecular biology.

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