Bendectin

Bendectin

[ben-dek-tin]
Bendectin, (known as Debendox in the UK and Diclectin in Canada) is a mixture of pyridoxine (Vitamin B-6), and doxylamine, is a drug prescribed to treat nausea and vomiting associated with morning sickness. It was voluntarily removed from the market in 1983 by its manufacturer, Merrell Dow Pharmaceuticals, following numerous lawsuits alleging that it caused birth defects, although an FDA panel concluded that no association between Bendectin and birth defects had been demonstrated. The most famous case involving the drug is Daubert v. Merrell Dow Pharmaceuticals (1993). These suits were led by flamboyant plaintiff attorney Melvin Belli.

The drug continues to be used in Europe under the same name, and no subsequent epidemiological studies have found any teratogenic effect.

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