Auranofin

Auranofin

[aw-ran-uh-fin]
Auranofin is a organogold compound classified by the World Health Organization as an antirheumatic agent.

It has the brand name Ridaura.

See also

External links

  • Cochrane review - "Auranofin versus placebo in rheumatoid arthritis"
  • Jeon K, Byun M, Jue D (2003). "Gold compound auranofin inhibits IkappaB kinase (IKK) by modifying Cys-179 of IKKbeta subunit.". Exp Mol Med 35 (2): 61–6.
  • Kim I, Jin J, Lee I, Park S (2004). "Auranofin induces apoptosis and when combined with retinoic acid enhances differentiation of acute promyelocytic leukaemia cells in vitro.". Br J Pharmacol 142 (4): 749–55.
  • Venardos K, Harrison G, Headrick J, Perkins A "Auranofin increases apoptosis and ischaemia-reperfusion injury in the rat isolated heart.". Clin Exp Pharmacol Physiol 31 (5-6): 289–94.
  • Hafejee A, Winhoven S, Coulson I (2004). "Jessner's lymphocytic infiltrate responding to oral auranofin.". J Dermatolog Treat 15 (5): 331–2.
  • Rigobello M, Folda A, Baldoin M, Scutari G, Bindoli A (2005). "Effect of auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase.". Free Radic Res 39 (7): 687–95.

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