An antidiuretic is an agent or drug that, administered to an organism, helps control body water balance through its effects on the urine output and kidneys. See diuretic. An example would be Vasopressin, a hormone which occurs naturally in the body, its primary function being an antidiuretic. It is secreted from the posterior pituitary gland.

Antidiuretics are the drugs that reduce urine volume, particularly in diabetes insipidus (DI) which is their primary indication. These are classified as:

1. Antidiuretic hormones: ADH, Vasopressin, Desmopressin, Lypressin, Terlipressin
2. Thiazide diuretics: Amiloride
3. Miscellaneous: Chlorpropamide, Carbamazepine

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