Many stimuli that one is at first neutral to, or even finds pleasant, can turn into annoyances from repeated continued exposure. One can often encounter this phenomenon with such media as popular music, commercials, and advertising jingles, which by their very nature are continually repeated over a period of weeks or months.
A study published in the International Journal of Conflict Management found that one's response to an annoyance, at least when the perceived cause is another person, escalate to more extreme levels as they go unresolved. It also found that one was more likely to blame the party who was causing the annoyance in the study, rather than one's self, for the annoyance as it escalated.
Psychological warfare can involve creating annoyances to distract and wear down the resistance of the target. For example, in 1993 the FBI played music "specifically selected for its irritation ability" on loudspeakers outside the Branch Davidian church in Waco, Texas in an attempt to bring about the surrender of David Koresh and his followers.
Too much annoyance can cause stress which can lead to heart problems.
1.) "Carla was so irksome at the party this evening!"
2.) Zamzam's obnoxiousness had everyone that knows her want to leave her at home when they go out.
3.) Darren's irritating behavior bothered many of the students trying to take the test.
4.) Leena's devilish act made made the hosts regret inviting her.
5.) Because of Derek's tendency to be bothersome, he was always left out.
In many comedic double acts humor comes from the annoyance that the comic's actions create for the comic foil. An act may also feature a person dealing violently with the annoying other (such as Punch and Judy)