Randolph left Gravesend on September 4, 1850, and Plymouth on the night of September 7 1850. The ship was chartered by the Canterbury Association, with Captain William Dale serving as the ship's captain. She arrived at Lyttelton 99 days later on December 16, 1850, with 34 cabin passengers, 15 intermediate and 161 steerage passengers.
She was lost on 25 June 1851, on a reef off Amber Island (Mapon). She had onboard a cargo of sugar for London, a large amount of money, and 254 Indian emigrants, for Port Louis. Nothing belonging to the vessel could be saved. Mr. Scott, an officer of the Madras Army, swam on shore, but died a moment after reaching it from exhaustion. Two European sailors, nine men (immigrants), ten women and three children were drowned.