Definitions

alpha granule

Platelet alpha-granule

In platelets, the term "alpha granules" is used to describe granules containing several growth factors (such as insulin-like growth factor 1, platelet-derived growth factor, TGFβ), platelet factor 4 which is a heparin-binding chemokine,) and other clotting proteins (such as thrombospondin and fibronectin and von Willebrand factor). The alpha granules express the adhesion molecule P-selectin. The other type of granules within platelets are called dense granules. A deficiency of alpha granules is known as grey platelet syndrome.

See also

External links

  • Harrison P, Cramer E (1993). "Platelet alpha-granules.". Blood Rev 7 (1): 52–62.

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