MACROCYTOSIS - 2 reference results
Macrocytosis is the enlargement of red blood cells with near-constant haemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories).
Causes
Most commonly (especially when the increase in size is mild, and just above normal range) the etiology is bone marrow dysplasia primary to alcohol abuse. Other causes may include:
- Megaloblastosis (Vitamin B12 or folate deficiency; or DNA synthesis-inbiting drugs)
- hypothyroidism
- reticulocytosis (commonly from hemolysis or a recent history of blood loss).
- liver disease
- myeloproliferative disease
Complications
No complications arise from macrocytosis itself and a prognosis will be determined from its aetiology.
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Last updated on Saturday October 04, 2008 at 10:11:45 PDT (GMT -0700)
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This article is licensed under the GNU Free Documentation License.
Last updated on Saturday October 04, 2008 at 10:11:45 PDT (GMT -0700)
View this article at Wikipedia.org - Edit this article at Wikipedia.org - Donate to the Wikimedia Foundation
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