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DOPAMINE-B-HYDROXYLASE - 2 reference results
What Is Bipolar Disorder?
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Dopamine beta hydroxylase
Dopamine β-hydroxylase (DBH) is an enzyme that converts dopamine to norepinephrine: Synonyms: Aromatic L-amino acid decarboxylase (tryptophan decarboxylase, 5-hydroxytryptophan decarboxylase, AAAD) is a lyase enzyme.

DBH is a 290 kDa copper-containing oxygenase consisting of four identical subunits, and its activity requires ascorbate as a cofactor. It is the only enzyme involved in the synthesis of small-molecule neurotransmitters that is membrane-bound, making norepinephrine and epinephrine the only transmitters synthesized inside vesicles. It is expressed in noradrenergic nerve terminals of the central and peripheral nervous systems, as well as in chromaffin cells of the adrenal medulla.

DBH is inhibited by disulfiram, tropolone, and, most selectively, by nepicastat.

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Last updated on Tuesday October 07, 2008 at 18:19:05 PDT (GMT -0700)
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What Is Bipolar Disorder?
Read About Bipolar Disorder Causes & Symptoms.
www.managingbipolar.com
Dopamine
Learn tips for diagnosing yourself and get news on latest treatments.
www.EverydayHealth.com
I Boosted My Serotonin
Without Chemicals. Find Out How I Did It Naturally!
Sponsored Results Viliftplus.com
Synosia begins Ph II post-traumatic stress trial.
Nov 10, 2008; Swiss firm Synosia Therapeutics has started a Phase IIa clinical trial with its dopamine b-hydroxylase inhibitor nepicastat...
Read more with a free trial on HighBeam.com »
Research on colitis immunology published by scientists at Nanchang University, Department of Gastroenterology.(Report)
May 06, 2009; Scientists discuss in 'Modulation of inflammatory response via alpha2-adrenoceptor blockade in acute murine colitis' new findings...
Read more with a free trial on HighBeam.com »
SCIENTISTS DISCOVER GENE FOR NURTURING.(Home Front)
Dec 28, 1997; Byline: Philip Cohen Copyright 1997 New Scientist Mothers who feel no attachment to their newborn babies may lack a neural...
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Genetic Findings in Attention Deficit Hyperactivity.
Mar 29, 1999; Mapping susceptibility loci in attention deficit hyperactivity disorder: Preferential transmission of parental alleles at DAT1,...
Read more with a free trial on HighBeam.com »
HighBeam Research, Inc. © Copyright 2009.

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