ALDOSTERONISM - 2 reference results
Hyperaldosteronism, also aldosteronism, is a medical condition where too much aldosterone is produced by the adrenal glands, which can lead to lowered levels of potassium in the blood.
Types
- : Primary hyperaldosteronism, often caused by an adrenal cortical adenoma (a tumor), is also known as Conn's syndrome.
- : Secondary hyperaldosteronism is due to overactivity of the renin-angiotensin system.
In endocrinology, the terms primary and secondary are used to describe the abnormality (e.g. elevated aldosterone) in relation to the defect, i.e. the tumor's location. The adjective primary refers to an abnormality that directly leads to pathology, i.e. aldosteronism is caused by the apparatus that generates aldosterone. Secondary refers to an abnormality that indirectly results in pathology through a predictable physiologic pathway, i.e. a renin producing tumor leads to increased aldosterone, as the body's aldosterone production is normally regulated by renin levels.
Symptoms
It can be asymptomatic, but the following symptoms can be present
- Fatigue
- Headache
- High blood pressure
- Hypokalemia
- Intermittent or temporary paralysis
- Muscle spasms
- Muscle weakness
- Numbness
- Polyuria
- Polydipsia
- Tingling
- Hypernatraemia
- Metabolic alkalosis
See also
Treatment
Treatment includes Spironolactone,a K+ sparing diuretic that works by acting as an aldosterone antagonistExternal links
Wikipedia, the free encyclopedia © 2001-2006 Wikipedia contributors (Disclaimer)
This article is licensed under the GNU Free Documentation License.
Last updated on Monday October 06, 2008 at 19:46:09 PDT (GMT -0700)
View this article at Wikipedia.org - Edit this article at Wikipedia.org - Donate to the Wikimedia Foundation
This article is licensed under the GNU Free Documentation License.
Last updated on Monday October 06, 2008 at 19:46:09 PDT (GMT -0700)
View this article at Wikipedia.org - Edit this article at Wikipedia.org - Donate to the Wikimedia Foundation
Copyright © 2009, Dictionary.com, LLC. All rights reserved.