Beta-alanyl-CoA ammonia-lyase

In enzymology, a beta-alanyl-CoA ammonia-lyase is an enzyme that catalyzes the chemical reaction

beta-alanyl-CoA rightleftharpoons acryloyl-CoA + NH3

Hence, this enzyme has one substrate, beta-alanyl-CoA, and two products, acryloyl-CoA and NH3.

This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is beta-alanyl-CoA ammonia-lyase (acryloyl-CoA-forming). This enzyme is also called beta-alanyl coenzyme A ammonia-lyase. This enzyme participates in beta-alanine metabolism and propanoate metabolism.


  • Stadtman ER "The enzymic synthesis of beta-alanyl coenzyme A". J. Am. Chem. Soc. 77 5765–5766.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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