• Abby Dalton, an American actress
• Abby Hoffman, a former Canadian track and field athlete.
• Abby Kelley, an American abolitionist and radical social reformer.
• Abby Aldrich Rockefeller, a prominent socialite and philanthropist and the second-generation matriarch of the renowned Rockefeller family
• Abby Rockefeller Mauzé, the first child and only daughter of Abby Rockefeller and John Davison Rockefeller, Jr.
• Abby Singer, a production manager and assistant director in film between the 1950s and the 1980s.
• Abby Travis, an American musician
• Abby Wambach, an Olympic medalist and professional soccer player.
• Abby Winters, an Australian-based pornographic or erotic model
• Abby Whiteside, an influential and controversial piano teacher
• Abby (singer), a female Japanese popular music artist
• Dear Abby, a syndicated personal advice column
• Tropical Storm Abby, the name used for three tropical cyclones in the Atlantic Ocean, and three tropical cyclones in the Western Pacific Ocean

It has also been used in fiction:

• Abby (film), a 1974 blaxploitation/horror film about a woman who is possessed by an African demon.
• Abby Holland (comics), a fictional comic book character who exists in the DC Universe.
• Abby Lockhart, a fictional medical doctor in the television series ER.
• Abby Maitland, a fictional character in the ITV sci-fi drama Primeval.
• Abby Sciuto, a fictional forensic scientist in the television series NCIS.
• Abby the Cow, a fictional character in the Nickelodeon animated series, Back at the Barnyard