| Train Name
| Railroad
| Train Endpoints
| Operated |
| Sacramento Daylight
| Southern Pacific
| Lathrop, CA-Sacramento, CA
| |
| Safety Express
| Chessie System
|
| 1980 - 1981 |
| Saint
| Santa Fe
| Los Angeles, CA-San Francisco, CA
| |
| St. Clair
|
| Chicago, IL-Detroit, MI
| |
| St. Louis Limited
| Wabash
| Detroit, MI-St. Louis, MO
| |
| St. Louis Mule
| Amtrak
| St. Louis, MO-Kansas City, MO
| |
| Salt City Express
|
| New York, NY-Syracuse, NY
| |
| Sam Houston Zephyr
| Burlington-Rock Island Railroad
| Fort Worth, TX - Houston, TX
| 1936-1966 |
| San Diegan
| Amtrak
| Santa Barbara, CA-San Diego, CA
| 1971-1999 |
| San Diegan
| Santa Fe
| Los Angeles, CA-San Diego, CA
| 1938-1971 |
| San Francisco Challenger
| Southern Pacific and Union Pacific
| Chicago, IL-San Francisco, CA
| 1935- |
| San Francisco Chief
| Santa Fe
| Chicago, IL-San Francisco, CA
| 1936-1971 |
| San Francisco Overland Limited
| Union Pacific
|
| |
| San Francisco Zephyr
| Chicago, Burlington & Quincy
| Chicago, IL-San Francisco, CA
| |
| San Joaquin Daylight
| Southern Pacific
| Los Angeles, CA-San Francisco, CA
| 1941-1971 |
| San Juan Express
| Denver & Rio Grande Western
| Alamosa, CO-Durango, CO
| 1937-1951 |
| San Joaquins
| Amtrak
| Bakersfield, CA-Oakland, CA
Bakersfield, CA-Sacramento, CA
| |
| Sangamon
| Illinois Terminal Railroad
|
| |
| Santa Fe De Luxe
| Santa Fe
| Chicago, IL-Los Angeles, CA
| 1911- |
| Scout
| Santa Fe
| Chicago, IL-Los Angeles, CA
| |
| Senator
| Pennsylvania Railroad and New Haven Railroad
| Washington, DC-Boston, MA
| |
| Senator
| Southern Pacific
| Oakland, CA-Sacramento, CA
| |
| Shasta Daylight
| Southern Pacific
| Oakland, CA-Portland, OR
| 1949-1967 |
| Shavano
| Denver & Rio Grande Western
| Salida, CO-Gunnison, CO
| 1937-1940 |
| Shawnee
|
| Chicago, IL-Carbondale, IL
| |
| Shelter Island Express
| Long Island Rail Road
| Long Island City-Greenport, New York
| Name dropped by LIRR sometime in the 1980s |
| Shenandoah
| Baltimore & Ohio Railroad
| Washington, DC-Cincinnati, OH
| |
| Shoppers Special
| Pere Marquette
| Chicago, IL-Grand Rapids, MI
| |
| Shoreland 400
| Chicago and North Western Railway
| Chicago, IL-Green Bay, WI
| |
| Shreveporter
| Louisiana and Arkansas
| Hope, AR-Shreveport, LA
| 1928-1961 |
| Silver Comet
| Pennsylvania and Seaboard Air Line
| New York, NY-Birmingham, AL
| |
| Silver Meteor
| Seaboard Air Line, later Amtrak
| New York, NY-Tampa, FL
New York, NY-Miami, FL
| 1939-present |
| Silver Star
| Seaboard Air Line, later Amtrak
| New York, NY-Tampa, FL
New York, NY-Miami, FL
| 1947-present |
| Silver Streak Zephyr
| Chicago, Burlington & Quincy
| Kansas City, MO-Lincoln, NE
| 1940- |
| Silverliner Service
|
| Philadelphia, Pennsylvania-Harrisburg, Pennsylvania
| |
| Skunk
| California Western Railroad
| Fort Bragg, California-Willits, California
| 1926- |
| Somerset Hills Express
| Lackawanna, Erie Lackawanna, Conrail, New Jersey Transit
| Hoboken, New Jersey-Gladstone, New Jersey
| 1940s-2001 |
| South Shore Express
| New York Central
| Chicago, IL-Toledo, OH
| |
| South Wind
| Florida East Coast and Pennsylvania
| Chicago, IL-Miami, FL
| 1940- |
| Southern Belle
| Kansas City Southern
| Kansas City, MO-New Orleans, LA
| 1940-1969 |
| Southern Crescent
|
| Boston, MA-New Orleans, LA
| |
| Southern Michigan Express
| Detroit and Mackinac Railway
| Detroit, MI-Cheboygan, MI
| |
| Southerner
| Pennsylvania and Southern
| New York, NY-New Orleans, LA
| 1941- |
| Southerner
| Missouri Pacific and Texas and Pacific
| Kansas City, MO-New Orleans, LA
| 1925- |
| Southwest Chief
| Amtrak
| Chicago, IL-Los Angeles, CA
| 1971-present |
| Southwest Limited
| Milwaukee Road
| Chicago, IL/Milwaukee, WI-Kansas City, MO
| 1903-1958 |
| Southwestern Limited
| New York Central
| New York, NY-St Louis, MO
| |
| Spirit of California
| Amtrak
| Sacramento, CA-Los Angeles, CA
| 1981?-1983 |
| Spirit of St. Louis
| Pennsylvania
| New York, NY-St Louis, MO
| |
| Sportsman
| Chesapeake and Ohio Railway
| Detroit, MI-Grand Rapids, MI
| |
| State House
| Amtrak
| Chicago, IL-St. Louis, MO
| |
| State of Maine Express
| New York, New Haven & Hartford Boston & Maine
| New York, NY- Portland, ME
| -1960 |
| Statesman
|
| Boston, MA-Washington, DC
| |
| Sundown
|
| New York, NY-Boston, MA
| |
| Sun Tan Special
| Southern Pacific
| San Francisco, CA-Santa Cruz, CA
| |
| Sunbeam
| Texas and New Orleans
| Houston, TX-Dallas, TX
| 1925-1955 |
| Sunset Limited
| Southern Pacific
| Los Angeles, CA-New Orleans, LA
| 1926-1971 |
| Sunset Limited
| Amtrak
| Los Angeles, CA-Orlando, FL
| 1971-present |
| Sunshine Special
| Missouri Pacific and Texas and Pacific
| St. Louis-San Antonio
| 1915-1948 |
| Super Chief
| Santa Fe
| Chicago, IL-Los Angeles, CA
| 1936-1971 |
| Train Name
| Railroad
| Train Endpoints
| Operated |
| Tennessean
| Missouri Pacific
| St. Louis, MO-Memphis, TN
| 1927-1948 |
| Tennessean
| Southern
| Washington, DC-Memphis, TN
| 1941-1968 |
| Texas Chief
| Santa Fe
| Chicago, IL-Galveston, TX
| 1936-1971 |
| Texas Chief (renamed Lone Star in 1974)
| Amtrak
| Chicago, IL-Houston, TX
| 1971-1974 |
| Texas Eagle
| Missouri Pacific
| St. Louis, MO - Galveston, TX / St. Louis, MO - San Antonio, TX / St. Louis, MO - El Paso, TX
| 1948- 1970 |
| Texas Eagle
| Amtrak
| Chicago, IL-San Antonio, TX
| |
| Texas Rocket
| Rock Island
| Fort Worth, TX-Houston, TX
Kansas City, MO-Dallas, TX
| 1937-1938
1938- |
| Texas Special
| Katy - Frisco
| St. Louis, MO-San Antonio, TX
| 1915-1965 |
| Texas Zephyr
| Chicago, Burlington & Quincy
| Denver, CO-Dallas, TX
| 1940- |
| Tex-Mex Express
| Texas Mexican Railway
| Corpus Christi, TX - Laredo, TX
| |
| Thoroughbred
| Monon Railroad
| Chicago, IL-Louisville, KY
| 1948- |
| Three Rivers
| Amtrak
| New York, NY-Chicago, IL
| 1995-2005 |
| Timberliner
| New York Central
| Detroit, MI-Mackinaw City, MI
| |
| Tippecanoe
| Monon Railroad
| Chicago, IL-Indianapolis, IN
| 1947- |
| Toledo - Detroit Express
| New York Central
| Detroit, MI-Toledo, OH
| |
| Tom Taber Express
| Lackawanna, Erie Lackawanna, Conrail, New Jersey Transit
| Hoboken, New Jersey-Dover, New Jersey
| 1940s-1996 |
| Torpedo
| Ann Arbor
| Frankfort, MI-Toledo, OH
| |
| Tourist Flyer
| Santa Fe
| San Francisco, CA-Chicago, IL
| |
| Trail Blazer
| Pennsylvania
| Chicago, IL-Pittsburgh, PA
| 1940- |
| Treasure Island Special
| Union Pacific
| Chicago, IL-San Francisco, CA
| 1939- |
| The Tulsan
| Santa Fe
| Chicago, IL-Tulsa, Oklahoma
| |
| Turboliner
| Amtrak
| New York, NY-upstate New York (exact route unknown)
Chicago, IL-Milwaukee, WI
Chicago, IL-Detroit, MI
| 1970s–1995
mid-1970s–early 1980s |
| Turbo (train)
| USDOT / New Haven Railroad, Penn Central, Amtrak
| New York, NY-Boston, MA
| 1968- |
| Twentieth Century Limited
| New York Central
| New York, NY-Chicago, IL
| 1902-1967 |
| Twilight Limited
| New York Central
| Chicago, IL-Detroit, MI
| |
| Twin Cities 400
| Chicago and North Western Railway
| Chicago,IL-Minneapolis,MN-Saint Paul, MN
| |
| Twin Cities Hiawatha
| Milwaukee Road
| Chicago, IL-St. Paul, MN
| 1935- |
| Twin Star Rocket
| Rock Island
| Minneapolis, MN-Houston, TX
| 1945-
|
| Valley 400
| Chicago and North Western Railway
| Chicago, IL-Green Bay, WI
| |
| Valley Eagle
| Missouri Pacific
| Brownsville, TX - Corpus Christi, TX - Houston, TX
| |
| Valley Express
| New York Central
| Chicago, IL-Detroit, MI
| |
| Valley Flyer
| Santa Fe
| Oakland, CA-Bakersfield, CA
| |
| Valley Forge
|
| New York, NY-Harrisburg, PA
| |
| Valpo Local
| Pennsylvania Railroad, Penn Central, Conrail, Amtrak
| Chicago, IL-Valparaiso, Ind
| 1869-1991 |
| Vermonter
| Amtrak
| Washington, DC-St. Albans, VT
| |
