According to the United States Census Bureau, the city has a total area of 5.9 square miles (15.3 km²), of which, 5.9 square miles (15.3 km²) of it is land and 0.17% is water.
There were 1,619 households out of which 37.4% had children under the age of 18 living with them, 55.9% were married couples living together, 12.2% had a female householder with no husband present, and 28.3% were non-families. 24.3% of all households were made up of individuals and 10.7% had someone living alone who was 65 years of age or older. The average household size was 2.57 and the average family size was 3.07.
In the city the population was spread out with 27.6% under the age of 18, 7.5% from 18 to 24, 30.3% from 25 to 44, 23.1% from 45 to 64, and 11.6% who were 65 years of age or older. The median age was 37 years. For every 100 females there were 92.5 males. For every 100 females age 18 and over, there were 87.2 males.
The median income for a household in the city was $38,581, and the median income for a family was $43,875. Males had a median income of $31,266 versus $24,634 for females. The per capita income for the city was $17,465. About 6.7% of families and 10.2% of the population were below the poverty line, including 14.7% of those under age 18 and 8.3% of those age 65 or over.
Vine Grove is home to two distinctly different eateries. One is the Tea House which offers Olde English style tea parties with specialty cookies and meals and the other is the Grapevine Cafe which offers home cooked goodness including a full selection of breakfast items and a full service lunch.