After another decline in the first half of the 16th century, the town has experienced explosive growth, thanks to an influx of Croatian settlers in 1540. Vištuk, thanks to its location at the merger of three creeks, has built several water reservoirs, the largest of which is surviving until today. By the end of the 16th Century, the village was one of the largest in the Červený Kameň county. In 1573, the town has built its Roman Catholic church of Holy Trinity, in the place of an older, Gothic church. Roughly at the same time, a smaller church was built, later rebuilt into a chapel.
The village's golden age took a sharp turn in 1705, when it was burned to the ground during the Battle of Budmerice, during the Francis II Rákóczi rebellion. The town was rebuilt, only to be burned down three more times in the 18th century. During that time, Anton Benčič, a Catholic priest, translator and one of the first proponents of the Slovak language, was born in Vištuk in 1745.
In the 19th and 20th century the village grew somewhat, mainly thanks to its vineyards. In 1920, the current name, Vištuk, was codified.
There is a school and a medical doctor in the village, the latter being present twice per week for adults and once per week for children.
The village has shifted its focus from small businesses to tourism. It sits on the so-called "Low Carpathian Mountains Wine Route", which connects all major wine producing towns in the area. The town's Muller Thurgau wines are considered to be of above average quality. The town's annual farmer's market ties into the wine making, and has been drawing many visitors to the village every year.
In addition, the village has created a natural area, including a unique nesting place for swallows. It consists of a sandstone wall with hundreds of holes that the swallows use for nesting in the spring.
The town's soccer club, established in 1931, is playing in Slovakia's lowest, sixth division soccer league. The soccer field is being occasionally used for other sporting events, such as a recent soccer tournament promoting ethnic tolerance.