Vellosimine dehydrogenase

10-deoxysarpagine + NADP⁺ $rightleftharpoons$ vellosimine + NADPH + H⁺

Thus, the two substrates of this enzyme are 10-deoxysarpagine and NADP⁺, whereas its 3 products are vellosimine, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 10-deoxysarpagine:NADP+ oxidoreductase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

References

• Pfitzner A, Krausch B and Stockigt J "Characteristics of vellosimine reductase, a specific enzyme involved in the biosynthesis of the Rauwolfia alkaloid sarpagine". Tetrahedron 40 1691–1699.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes