In
human genetics,
Haplogroup F is a
Y-chromosome haplogroup. This haplogroup and its
subclades contain more than 90% of the world's extant male population, including almost everyone outside of
Africa, except for
Tibet,
Kazakhstan,
Mongolia,
Japan,
Polynesia, and communities of
indigenous Australians, while also including many men within those regions.
Origins
This ancient haplogroup may have first appeared in
North Africa, the
Levant, or the
Arabian Peninsula as much as 50,000 years ago: 50,300±6500, Hammer and Zegura 2002; 48,000(38,700-55,700). It is sometimes believed to represent a "second-wave" of expansion out of
Africa. However, the location of this lineage's first expansion and rise to dominance appears to have been in ice age
Ethiopia or the
Middle East or somewhere close to it within
South Asia India ; all of Haplogroup F's descendant haplogroups also show a pattern of radiation from South Asia (haplogroups H and K) or the Middle East (haplogroups G and IJ).
Several lineages derived from Haplogroup F appear to have migrated into Africa from a homeland in Southwest Asia sometime during prehistory. Y-chromosome haplogroups associated with this hypothetical "Back to Africa" migration include J, R1b, and T. The occurrence of haplogroups J, R1b, and T among precolonial populations of Africa is highly correlated with the distribution of languages of the Afro-Asiatic phylum.
Derivative haplogroups
Haplogroup F is an ancestral haplogroup to Y-chromosome haplogroups
G (M201),
H (M52),
I (M170),
J (12f2.1), and
K (M9) along with K's descendant haplogroups (
L,
M,
N,
O,
P,
Q, and
R).
Besides the major clades G, H, IJ, and K, other patrilines derived from Haplogroup F-M89 can still be detected at a very low frequency among many populations of the southern fringe of Eurasia and Oceania, from Portugal in the west to Korea and the Malay Archipelago in the east. India, Korea, and the Ailao Mountains of Yunnan Province in southwestern China appear to be the only regions where such lineages, which are grouped for convenience as Haplogroup F*, comprise a significant portion of the Y-chromosome diversity of the modern populations. Haplogroup F* Y-chromosomes have been found to be particularly common among the Kucong or Yellow Lahu, a group of hunter-gatherers who live in the Ailao Mountains of Yunnan. Korean F* probably reflects a rare brother clade of haplogroups G, H, IJ, and K that may have experienced a geographically limited expansion during historical times, as such Haplogroup F* Y-chromosomes have not been found among the neighboring Japanese.
Subclades
The rare clades F1 (P91, P104) and F2 (M427, M428) have been identified among some of the Haplogroup F-M89 Y-chromosomes that formerly were classified as F*. The extent of the distribution of haplogroups F1 and F2 is not yet known for certain, but these two clades, like F*, seem to occur only at a very low frequency among modern human populations and primarily only among populations of India and East Asia.
The subclades of Haplogroup F with their defining mutation(s), according to the 2006 ISOGG tree (abbreviated for clarity to a maximum of five steps away from the root of Haplogroup F):
- F (M89, M213/P137, M235, P14, P133, P134, P135, P136, P138, P139, P140, P141, P142, P145, P146, P148, P149, P151, P157, P158, P159, P160, P161, P163, P166, P187)
- F*
- F1 (P91, P104)
- F2 (M427, M428) Found at a low frequency in East Asia
- G (M201) Most common today in some peoples of the Caucasus; also found at a low frequency throughout Europe, the Near East, Central Asia, and Southern Asia
- G*
- G1 (M285, M342)
- G2 (P15)
- G3 (M287)
- G4
- G5 (M377) Almost exclusively found in low numbers among Ashkenazi Jews
- H (M69) Generally limited to South Asia; typical of Central, East, and South Indian population as well as the Roma of Europe
- H*
- H1 (M52)
- H1*
- H1a (M82)
- H1a*
- H1a1 (M36, M197)
- H1a2 (M97)
- H1a3 (M39, M138)
- H1b (M370)
- H2 (Apt)
- IJ (M429, P123, P124, P125, P126, P127, P129, P130, S2, S22) per ISOGG 2008
- I (M170, P19, M258, P38, P212, U179) Haplogroup I notation updated to ISOGG 2008
- I*
- I1 (M253, M307, M450/S109, P30, P40, S62, S63, S64, S65, S66, S107, S108, S110, S111) (formerly I1a) Typical of populations of Scandinavia and Northwest Europe, with a moderate distribution throughout Eastern Europe
- I1*
- I1a (M21) (formerly I1a2)
- I1b (M227) (formerly I1a1) Appears to be limited to a marginally low frequency of approximately 1% among Slavic and Uralic peoples of Eastern Europe; also detected in a single Lebanese man
- I1b1 (M72) (formerly I1a1a)
- I1c (P109)
- I1d (P259)
- I2 (M438/P215/S31) (formerly I1b)
- I2*
- I2a (P37.2) (formerly I1b1) Typical of the South Slavic peoples of the Balkans, especially the populations of Bosnia and Croatia; also found with high haplotype diversity values, but lower overall frequency, among the West Slavic populations of Slovakia and the Czech Republic; a node of elevated frequency in Moldavia correlates with that observed for Haplogroup I2a (but not for Haplogroup I1)
- I2a*
- I2a1 (M423)
- I2a1*
- I2a1a (P41.2/M359.2) (formerly I1b1a) Typical of the population of the so-called "archaic zone" of Sardinia; also found at low frequencies among populations of Southwest Europe, particularly in Castile, Béarn, and the Basque Country
- I2a2 (M26) (formerly I1b1b)
- I2a2*
- I2a2a (M161) (formerly I1b1b1)
- I2b (M436/P214/S33, P216/S30, P217/S23, P218/S32) (formerly I1b2)
- I2b*
- I2b1 (M223, P219/S24, P220/S119, P221/S120, P222/U250/S118, P223/S117) (formerly I1b2a - old I1c) Occurs at a moderate frequency among populations of Northwest Europe, with a peak frequency in the region of Lower Saxony in central Germany; minor offshoots appear in Moldavia and Russia (especially around Vladimir, Ryazan, Nizhny Novgorod, and the Republic of Mordovia)
- I2b1*
- I2b1a (M284) (formerly I1b2a1) Generally limited to a low frequency in Great Britain
- I2b1b (M379) (formerly I1b2a2)
- I2b1c (P78) (formerly I1b2a3)
- I2b1d (P95) (formerly I1b2a4)
- J (12f2.1, M304, S6, S34, S35)
- J*
- J1 (M267) Typical of populations of Dagestan, Mesopotamia, the Levant, Arabia, and Semitic-speaking populations of North Africa and East Africa, with a moderate distribution throughout Southwest Asia
- J1*
- J1a (M62)
- J1b (M365)
- J1c (M367, M368)
- J1d (M369)
- J1e (M390)
- J2 (M172) Typical of populations of Southern Europe, Turkey, northern Iraq, Iran, and the Caucasus, with a moderate distribution throughout Southwest Asia, Central Asia, South Asia, and North Africa
- J2*
- J2a (M410)
- J2a*
- J2a1 (DYS413≤18)
- J2a2 (M340)
- J2b (M12, M314, M221)
- J2b*
- J2b1 (M102) Mainly found in the Balkans, Greece, and Italy (possibly from Ancient Greeks)
- K (M9) Typical of populations of northern Eurasia, eastern Eurasia, Melanesia, and the Americas, with a moderate distribution throughout Southwest Asia, northern Africa, and Oceania
- K*
- K1 (M147)
- K2 (P60)
- K3 (P79) Found in Melanesia
- K4 (P261, P263)
- L (M11, M20, M22, M61, M185, M295) Typical of populations of Pakistan
- L*
- L1 (M27, M76) Typical of Dravidian castes of India and Sri Lanka, with a moderate distribution among Indo-Iranian peoples of South Asia
- L2 (M317) Found at low frequency among populations of Central Asia, Southwest Asia, and Southern Europe
- L2*
- L2a (M274)
- L2b (M349)
- L3 (M357) Frequently found among Burusho and Pashtuns, with a moderate distribution among the general Pakistani population
- L3*
- L3a (PK3) Found among Kalash
- M (P256)
- NO (M214)
- NO*
- N (LLY22g, M231)
- N*
- N1 (M128) Found at a low frequency among Manchu, Sibe, Manchurian Evenks, Koreans, northern Han Chinese, Buyei, and some Turkic peoples of Central Asia
- N2 (P43) Typical of Northern Samoyedic peoples; also found at low to moderate frequency among some other Uralic peoples, Turkic peoples, Mongolic peoples, Tungusic peoples, and Eskimos
- N3 (Tat (M46)) Typical of the Sakha and Uralic peoples, with a moderate distribution throughout North Eurasia
- O (M175)
- P (92R7, M45, M74, (N12), P27)
- P*
- Q (M242)
- Q*
- Q1 (P36.2)
- Q1*
- Q1a (MEH2)
- Q1b (M378) Found at low frequency among samples of Hazara and Sindhis
- R (M207 (UTY2), M306 (S1), S4, S8, S9)
- S (M230) Typical of populations of the highlands of New Guinea; also found at lower frequencies in adjacent parts of Indonesia and Melanesia
- T (M70, M184, M193, M272) Found in a significant minority of Arabs, Ethiopians, Somalians, and Fulbe; also found at low frequency throughout Southwest Asia, Northern Africa, Southern Europe, and parts of India
References
External links