Uspallata Pass, c.12,500 ft (3,810 m) high, over the Andes between Mendoza, Argentina, and Santiago, Chile. A trail—and later a rough road—for men and pack animals was used before the Transandine Railway (1910-82) was built. The Pan-American Highway now runs near the pass, through the Christ the Redeemer Tunnel. In 1817 José de San Martín sent part of his patriot army through the pass to fight the Spanish royalists in Chile. The Christ of the Andes statue stands in the pass. Mt. Aconcagua towers to the north. The pass is also known as Paso de la Cumbre [Summit Pass] and Paso Los Libertadores [Liberators Pass].

The Uspallata Pass or Bermejo Pass is an Andean pass which provides a route between the wine-growing region around the Argentine city of Mendoza and Santiago the Chilean capital situated in the central Chilean valley. The pass has been used since Colonial times as the most direct link between the Pacific seaport of Valparaiso and the Atlantic port of Buenos Aires, avoiding the 11 day, journey by sea, via Cape Horn, between the two ports. Reaching a maximum altitude of about , the pass runs between the peaks of the Aconcagua to the north and the Tupungato to the south.

Today, the Uspallata Pass provides a major transportation link between Chile and Argentina and a railroad tunnel built by the now defunct Transandine Railway (1910–1982) runs underneath. The Pan-American Highway runs through the near-by Cristo Redentor Tunnel (in Spanish: Paso Internacional Cristo Redentor) and a monument, Christ the Redeemer of the Andes ("Cristo Redentor de los Andes" in Spanish) is located at the pass.