Klakring was laid down on 19 February 1982 by the Bath Iron Works Corp. Bath, Maine; launched on 18 September 1982; and commissioned on 20 August 1983.
As of 2006, Klakring is homeported at NAVSTA Mayport, Florida, and is part of Destroyer Squadron 14.
Klakring participated in Operation Earnest Will in the Persian Gulf in 1987 as the first air-capable, air-embarked ship. Klakring participated in Operation Prime Chance in the Persian Gulf during the "Tanker War". Klakring is one of the surface combatants in Larry Bond's 1993 technothriller ''Cauldron.