DNA and RNA have a deoxyribose and ribose sugar backbone, respectively, whereas TNA's backbone is composed of repeating threose units linked by phosphodiester bonds. The threose molecule is easier to assemble than ribose making it a possible precursor to RNA.
DNA-TNA hybrid chains have been made in the laboratory using DNA polymerase.
TNA can specifically base pair with RNA and DNA; this capability and chemical simplicity suggests that TNA could have preceded RNA as genetic material.
Wipo Publishes Patent of Quark Pharmaceuticals for "Double Stranded Oligonucleotide Compounds Comprising Positional Modifications" (Israeli, American Inventors)
Jun 16, 2012; GENEVA, June 16 -- Publication No. WO/2012/078536 was published on June 14. Title of the invention: "DOUBLE STRANDED...