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Tegafur-uracil
Tegafur-uracil
Tegafur-uracil is a chemotherapy drug used in the treatment of cancer, primarily bowel cancer. It is also called UFT or UFUR.
UFT is a first generation DIF, or DPD (DihydroPyrimidine Dehydrogenase) Inhibitory Flouropyrimidine drug. UFT is an oral agent with combines uracil, a competitive inhibitor of DPD, with the 5-FU prodrug tegafur in a 4:1 molar ratio. Excess uracil competes with 5-FU for DPD, thus inhibiting 5-FU catabolism.
It is marketed by Merck Serono.
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This article is licensed under the GNU Free Documentation License.
Last updated on Friday July 04, 2008 at 10:40:44 PDT (GMT -0700)
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This article is licensed under the GNU Free Documentation License.
Last updated on Friday July 04, 2008 at 10:40:44 PDT (GMT -0700)
View this article at Wikipedia.org - Edit this article at Wikipedia.org - Donate to the Wikimedia Foundation
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