| Letter | Sign | Name | Field | Associated conditions | External link (if no internal link) | Descriptor | |
| A | Aaron sign | Charles Dettie Aaron | surgery | appendicitis | epigastric pain with pressure on McBurney's point | ||
| A | Abadie's sign | Jean Marie Charles Abadie | endocrinology | Graves' disease | levator palpebrae superioris spasm | ||
| A | Abadie's symptom | Joseph Louis Irenée Jean Abadie | neurology | tabes dorsalis | absence of pain on Achilles tendon pressure | ||
| A | Abderhalden reaction | Emil Abderhalden | obstetrics | pregnancy | serum reaction;obsolete | ||
| A | Abelin reaction | Isaak Abelin | infectious disease | syphilis | presence of arsenical anti-syphilitic;obsolete | ||
| A | Addis count | Thomas Addis | nephrology | pyelonephritis | (needed) | quantitative cells and casts in 24hr. urine | |
| A | Adie pupil | William John Adie | neurology | ||||
| A | Adson's sign | Alfred Adson | vascular surgery | thoracic outlet syndrome | obliteration of radial pulse with manouevres | ||
| A | Alexander's law | ? | neurology, neurosurgery, ENT | vestibular lesions | describes nystagmus in vestibular lesions | ||
| A | Allen's test | Edgar Van Nuys Allen | vascular surgery, critical care(1) | arterial supply of the hand | tests for presence of palmar ulnar-radial anastomosis (palmar arch) | ||
| A | Apley grind test | Alan Graham Apley | orthopaedic surgery | meniscal lesions | manouevres to elicit knee pain | ||
| A | Argyll Robertson pupils | Douglas Moray Cooper Lamb Argyll Robertson | neurology | neurosyphilis | light-near dissociation | ||
| A | Arneth count | Josef Arneth | haematology, nutrition | folate deficiency | lobulation of neutrophil nuclei | ||
| A | Aschheim-Zondek test | Selmar Aschheim, Bernhard Zondek | obstetrics | normal pregnancy | oestral reaction in mouse injected with pregnant urine | ||
| A | Aschoff body | Karl Albert Ludwig Aschoff | rheumatology, pathology | rheumatic fever | foci of interstitial inflammatiuon in the myocardium and elsewhere | ||
| A | Ashby techniques | Winifred Ashby | haematology, pathology | haemolysis | (needed) | agglutination test for eryhrocyte survival | |
| A | Auberger's blood group | Auberger (patient) | haematology | normal physiology | (needed) | Aua antigen | |
| A | Auenbrugger's sign | Josef Leopold Auenbrugger | cardiology | pericardial effusion | bulging epigastrium | ||
| A | Auer rods | John Auer | hematology | acute myeloid leukemia | cytoplasmic inclusions in myeloblasts | ||
| A | Auspitz's sign | Heinrich Auspitz | dermatology | psoriasis | punctate bleeding when scales are scraped | ||
| A | Austin Flint murmur | Austin Flint | cardiology | aortic insufficiency | mid-diastolic rumble heard at apex | ||
| B | Babinski sign | Joseph Babinski | neurology | abnormal plantar reflex | dorsiflexion of the hallux with fanning of the remaining phalanges upon soft stimulation of the lateral plantar surface of the foot | ||
| B | Bainbridge reflex | Francis Arthur Bainbridge | cardiology | normal physiology | increase in heart rate with increase in circulating blood volume | ||
| B | Balbiani rings | Edouard-Gérard Balbiani | (needed) | ||||
| B | Ballance's sign | Charles Alfred Ballance | general surgery | abdominal/splenic trauma | (needed) | percussive dullness left flank, LUQ, percussive rsonance right flank | |
| B | Bárány test | Robert Bárány | ENT,neurology | vertigo, vestibulsr dysfunction | (needed) | nystagmus elicited by hot or cold irrigation of ear canal | |
| B | Barlow's maneuver | Sir Thomas Barlow, 1st Baronet | paediatrics, orthopaedic surgery | hip dysplasia | (needed) | dislocation on adduction of hip | |
| B | Bart hemoglobin | Barts Hospital | Obstetrics, pathology | indicates a specific cause of death in some stillborns | (needed) | Loss of all four alpha-globin genes (total alpha-thalassemia) leads to severely anemic stillborn babies with small amounts of an abnormal hemoglobin composed of four gamma sub-units (Bart's Hemoglobin) | |
| B | Bastian-Bruns sign | Henry Charlton Bastian, Ludwig Bruns | neurology | spinal cord transection | (needed) | loss of muscle tone and reflexes below lesion level | |
| B | Battle's sign | William Henry Battle | neurosurgery/traumatology | basal skull fracture | mastoid ecchymosis | ||
| B | Beau's lines | Joseph Honoré Simon Beau | dermatology, internal medicine | multiple, including trauma | transverse ridges on nails | ||
| B | Beck's triad | Claude Schaeffer Beck | cardiology | cardiac tamponade | hypotension, increased central venous pressure (JVP), distant heart sounds | ||
| B | Becker's sign | Otto Heinrich Enoch Becker | ophthalmology, endocrinology | thyrotoxicosis | (needed) | visible pulsation of retinal arteries | |
| B | Beevor's sign | Charles Edward Beevor | neurology, neurosurgery | spinal trauma at T10, als,fsmd | caudal movement of navel on cervical flexion | ||
| B | Bekhterev- Jacobsohn reflex | Vladimir Bekhterev, Louis Jacobsohn | neurology | stroking dorsal radial skin, with forearm in supination, elicits wrist and finger flexion | |||
| B | Bekhterev-Mendel reflex | Vladimir Bekhterev, Kurt Mendel | neurology | pyramidal tract lesions | (needed) | toe flexion on percussion of dorsum of foot | |
| B | Bence Jones protein | Henry Bence Jones | hematology | multiple myeloma | |||
| B | Benedict solution | Stanley Rossiter Benedict | endocrinology | diabetes mellitus | reagent for presence of monosaccharides | ||
| B | Berger wave (rhythm) | Hans Berger | neurology | normal physiology | (needed) | electroencephalographic alpha wave | |
| B | Bezold-Jarisch reflex | Albert von Bezold, Adolf Jarisch | pharmacology, toxicology | effect of certain alkaloids | (needed) | apnea, bradycardia, hypotension | |
| B | Bielschowsky's tilt test | Alfred Bielschowsky | neurology, ophthalmology | lesions of cranial nerve iv | (needed) | test for palsy of superior oblique | |
| B | Bing's sign | Paul Robert Bing | neurology,ENT | hearing loss | (needed) | see Rinne test | |
| B | Biot's respiration | C. Biot | neurology | brain stem herniation | quick shallow respirations followed by period of apnea | ||
| B | Bitot's spots | Pierre Bitot | ophthalmology | vitamin A deficiency | spots of keratin deposition in the conjunctiva | ||
| B | Bjerrum scotoma | Jannik Peterson Bjerrum | ophthalmology | glaucoma | (needed) | comet shaped visual field defect,extending temporally from the physiological blind spot | |
| B | Blumberg sign | Jacob Moritz Blumberg | surgery | peritonitis | rebound tenderness | ||
| B | Boas' point | Ismar Isidor Boas | gastroenterology | gastric ulcer | (needed) | dermal hyperaesthesia just left of T12 | |
| B | Boas' sign | Ismar Isidor Boas | gastroenterology | acute cholecystitis | dermal hyperaesthesia at inferior angle of R scapula | ||
| B | Bodansky unit | Meyer Bodansky | (needed) | ||||
| B | Boston's sign | L.N. Boston | ophthalmology, endocrinology | thyrotoxicosis | spasmodic ptosis on downward gaze | ||
| B | Bouchard's nodes | Charles-Joseph Bouchard | rheumatology | osteoarthritis | bony outgrowths on dorsa of proximal interphalangeal joints | ||
| B | Bracht-Wachter bodies | Erich Franz Eugen Bracht, H. Wächter | cardiology | infective endocarditis | yellow-white spots in the myocardium | ||
| B | Branham's sign | Henry Branham | (needed) | pressing on proximal portion of AV fistula results in bradycardia | |||
| B | Braxton Hicks contraction | John Braxton Hicks | obstetrics | normal pregnancy | "false labour". sporadic contractions beginning as early as mid 1st trimester | ||
| B | Brewer infarcts | George Emerson Brewer | nephrology, pathology | pyelonephritis | (needed) | dark red wedge shaped areas on kidney section resembling infarcts | |
| B | Broadbent inverted sign | Sir William Broadbent, 1st Baronet | cardiology | L atrial hypertrophy | (needed) | systole palpable in posterior chest wall | |
| B | Brissaud's reflex | Édouard Brissaud | neurology | (needed) | plantar stimulation elicits contraction of tensor fasciae latae | ||
| B | Broadbent sign | Sir William Broadbent, 1st Baronet | cardiology | adhesive pericarditis | (needed) | recession of L inferior intercostal spaces | |
| B | Broca aphasia | Paul Broca | neurology, neuropsychology | developmental or other pathology of various frontal cortical areas | expressive aphasia | ||
| B | Brodie-Trendelenburg percussion test | Sir Benjamin Collins Brodie,bt., Friedrich Trendelenburg | general medicine, surgery | varicose veins | superficial vein is percussed proximally;if impulse is felt over vein distally, valvular incompetence is present. | ||
| B | Brodie-Trendelenburg test | Benjamin Collins Brodie, Friedrich Trendelenburg | general medicine,surgery | varicose veins | identifies level of valvular incompetence | ||
| B | Brudzinski neck sign | Józef Brudziński | neurology | meningitis | neck flexion elicits hip and knee flexion | ||
| B | Brudzinski cheek sign | Józef Brudzinski | neurology | meningitis | pressure beneath zygoma elicits flexion of forearm | ||
| B | Brudzinski symphiseal sign | Józef Brudzinski | neurology | meningitis | pressure over symphisis pubis elicits knee, hip flexion and leg abduction | ||
| B | Brudzinski reflex | Józef Brudzinski | neurology | meningitis | passive flexion of knee to abdomen elicits flexion of contralateral hip and knee | ||
| B | Bruit de Roger | Henri-Louis Roger | paediatric cardiology | ventricular septal defect | (needed) | loud pansystolic murmur | |
| B | Bruns ataxia | Ludwig Bruns | neurology | frontal lobe lesions | (needed) | difficulty moving feet in contact with floor, tendency to fall backwards | |
| B | Brushfield spots | Thomas Brushfield | ophthalmology, genetics | Downs' syndrome or non-pathological | greyish-white spots at periphery of iris | ||
| B | Burton line | Henry Burton | toxicology | lead poisoning | NEJM 354:e21 5/18/06 | Blue discolouration of the gingival border | |
| C | Cabot rings | Richard Cabot | hematology | lead poisoning, anaemias | threadlike strands in erythrocytes | ||
| C | Caput medusae | Medusa | gastroenterology, surgery | portal hypertension | distended veins radiating from umbilicus | ||
| C | Cardarelli's sign | Antonio Cardarelli | cardiology, thoracic surgery | aortic arch dilatation or aneurysm, mediastinal tumour | left displacement of trachea elicits palpable pulsation of same | ||
| C | Carey Coombs murmur | Carey Coombs | cardiology,rheumatology | rheumatic fever | (needed) | mid-diastolic rumble | |
| C | Carnett's test | John Carnett | primary care, surgery | abdominal mass and/or pain | Am J Med Sci 174 (1927): 579–599 | supine patient lifts head from bed;↑ pain - abdominal wall ;↓ pain - intraperitoneal | |
| C | Carvallo sign | José Carvallo | (needed) | ||||
| C | Casal collar | Gaspar Casal | nutrition | pellagra (niacin deficiency) |
| widely variable collar of dermatitis characteristically in c3,c4 dermatomes | |
| C | Casoni test | Tommaso Casoni | infectious disease, tropical medicine | hydatid disease | (needed) | intradermal antigen | |
| C | Celsus signs of inflammation | Aulus Cornelius Celsus | various | inflammation | 1. Rubor (redness) 2. Tumor (swelling)3. Caldor (heat) 4. Dolor (pain) | ||
| C | Chaddock reflex | Charles Gilbert Chaddock | neurology | pyramidal lesions, corticospinal tract lesions | extension of big toe with stimulation of skin over lateral malleolus | ||
| C | Chadwick sign | James Read Chadwick | obstetrics | pregnancy | cyanosis of vulva, vagina and cervix | ||
| C | Charcot's triad | Jean-Martin Charcot | surgery | ascending cholangitis | jaundice, fever and chills, RUQ pain | ||
| C | Charcot's Triad | Jean-Martin Charcot | neurology | multiple sclerosis | nystagmus, intention tremor ,staccato speech | ||
| C | Charcot-Leyden crystals | Jean-Martin Charcot, Ernst Viktor von Leyden | pathology | any disorder characterized by eosinophil proliferation, e.g. ascariasis | lysophospholipase crystals in various tissues | ||
| C | Cheyne-Stokes respiration | John Cheyne, William Stokes | palliative care | ||||
| C | Churchill-Cope reflex | Edward Delos Churchill, Oliver Cope | (needed) | ||||
| C | Chvostek's sign | František Chvostek | endocrinology | hypocalcemia | tapping over facial nerve elicits abnormal muscle contraction(s) | ||
| C | Claybrook sign | Edwin Claybrook | emergency medicine, surgery | blunt abdominal trauma | (needed) | heart and/or breath sounds heard through abdominal wall indicate rupture of viscus | |
| C | Clutton's joints | Henry Hugh Clutton | paediatrics | hereditary syphilis | (needed) | painless symmetrical hydrarthroses, particularly of the knees | |
| C | Codman's triangle | Ernest Armory Codman | oncology, orthopaedic surgery, radiology | osteosarcoma, ewing's sarcoma | triangular subperiosteal growth | ||
| C | Comby sign | Jules Comby | paediatrics | rubeola | (needed) | whitish patches on gingiva and buccal mucosa | |
| C | Coombs test | Robin Coombs | hematology | hemolytic anemia | |||
| C | Coons fluorescent antibody method | Albert Coons | (needed) | ||||
| C | Corrigan pulse | Dominic John Corrigan | cardiology | aortic insufficiency | carotid pulsations with abrupt ascending and descending phases | ||
| C | Councilman body | William Councilman | infectious disease | yellow fever, viral haemorrhagic fevers | eosinophilic globules in liver | ||
| C | Courvoisier's law | Ludwig Georg Courvoisier | gastroenterology | obstructive jaundice | palpable gall bladder w/ painless jaundice unlikely to be cholelithiasis | ||
| C | Crichton-Browne sign | Sir James Crichton-Browne | neuropsychiatry | 'general paresis' | (needed) | tremor at corners of mouth and of outer canthus | |
| C | Crowe sign | Samuel Crowe | dermatology (?) | neurofibromatosis type I | axillary freckling | ||
| C | Cruveilhier-Baumgarten bruit | Jean Cruveilhier, Paul Clemens von Baumgarten | internal medicine | cirrhosis;portal hypertension | (needed) | periumbilical hum | |
| C | Cullen's sign | Thomas Cullen | surgery | intraabdominal haemorrhage | ecchymosis around umbilicus predicts onset of acute pancreatitis | ||
| C | Curschmann spirals | Hans Curschmann | |||||
| C | Cushing's triad | Harvey Cushing | neurology | raised intracranial pressure | elevated systolic bp, bradycardia, irregular respiration | ||
| D | Dagher Maneuver | Nabil Dagher | trauma surgery | penetrating pelvic trauma | bimanual palpation of foreign object lodged in pelvis with one digit in an incision lateral to the anus and the other digit inserted in the rectum | ||
| D | Dahl's sign | ? | pulmonology | COPD |
| pigmented calluses on anterior surface of thighs (from leaning on elbows) | |
| D | Dalrymple sign | John Dalrymple | ophthalmology, endocrinology | thyrotoxicosis | widened palpebral opening | ||
| D | Dance's sign | Jean-Baptiste Hippolyte Dance | (paediatric)surgery | ileo-cecal intussusception | empty LLQ (retracted iliac fossa) | ||
| D | Darier's sign | ? | allergy,dermatology | urticaria pigmentosa | dermatographia | ||
| D | Dawson's fingers | james walker dawson | neurology | multiple sclerosis |
| characteristic fingerlike appearance of lateral ventricle on mri, ct, or at autopsy | |
| D | De Musset's sign | ? | cardiology | aortic insufficiency | head nodding in time with heartbeat | ||
| D | Dennie's lines also Dennie's fold | ? | dermatology | atopic dermatitis | ( )
| accentuated fold in the inferior palpebrum | |
| D | Destot's sign | ? | orthopaedic surgery | pelvic fracture |
| ecchymosis superior to inguinal ligament, in scrotum or of thigh | |
| D | Dix-Hallpike test | ? | general medicine | Otoconia crystals in inner ear | Elicitation of extreme vertigo upon lateral movement of a patient's head when lying in a supine position is indicative of a condition known as Benign Paroxysmal Positional Vertigo (BPPV) | ||
| D | Döhle bodies - | Karl Gottfried Paul Döhle | pathology | various including trauma and neoplasm | basophilic inclusions in peripheral cytoplasm of neutrophils | ||
| D | Doi's sign | ? |
| ||||
| D | Dunphy sign | ? | surgery | appendicitis |
| increase in abdominal pain on coughing | |
| D | Duroziez's sign | ? | cardiology | aortic insufficiency | double bruit heard over femoral artery when it is compressed distally (see Traube's sign) | ||
| E | Elschnig spots | Anton Elschnig | ophthalmology | hypertensive retinopathy | |||
| E | Epstein's pearls | ? | paediatrics | normal newborn | cystic papules on palate | ||
| E | Ewart's sign | ? | cardiology | pericardial effusion | percussive dullness, aegophony and bronchial breath sounds at L scapular tip | ||
| F | Finkelstein's test | Harry Finkelstein | rheumatology | DeQuervain's tenosynovitis | |||
| F | Forschimer spots | ? | (needed) | ||||
| F | Fothergill's sign | ? | |||||
| F | Fox's sign | George Henry Fox | gastroenterology | haemorrhagic pancreatitis | (needed) | ecchymosis of inguinal ligament (blood tracks retroperitoneally) | |
| F | Frank's sign | ? | (needed) | ||||
| F | Friedreich's sign | ? | cardiology | constrictive pericarditis, tricuspid insufficiency | collapse of distended neck veins at diastole | ||
| F | Froment's sign | Jules Froment | neurology | ulnar nerve palsy | patient required to hold paper between thumb and palm (against attempt to withdraw);ability to do so is assessed | ||
| Gaenslen's test | |||||||
| G | Gallavardin phenomenon | ? | cardiology | aortic stenosis | (needed) | dissociation of musical and noisy elements in ejection murmur | |
| G | Gandy-Gamma nodules | ? | (needed) | ||||
| G | Gerhardt's sign | Carl Jakob Adolph Christian Gerhardt |
| controversial: see references | |||
| G | Goetz sign | ? | (needed) | ||||
| G | Gond's maneuver | ? | (needed) | ||||
| G | Goodell's sign | ? | obstetrics | ||||
| G | Goodsall's rule | ? | gastroenterology, general surgery | anal fistula | anatomical relationships, differentiation of fistula types | ||
| G | Gordon's maneuver | ? | (needed) | ||||
| G | Gottron's papules | ? | rheumatology | dermatomyositis | roseate discolouration over knuckles | ||
| G | Gowers' sign (Gowers' maneuver) | William Richard Gowers | neurology | muscular dystrophy | |||
| G | Graham Steell murmur | ? | (needed) | ||||
| G | Grey Turner's sign | George Grey Turner | surgery | retroperitoneal hemorrhage | flank ecchymosis | ||
| G | Griffith's sign | ? | (needed) | ||||
| G | Grotton's lesions | ? | (needed) | ||||
| G | Gunn's sign | ? | (needed) | ||||
| H | Hamman's sign | Louis Hamman | thoracic surgery | oesophageal perforation w/ pneumomediastinum | crepitus in sync w/ heartbeat but not respiration | ||
| H | Hampton's hump | Aubrey Otis Hampton | pulmonolgy, radiology | pulmonary embolus w/ infarct | wedge shaped consolidation at periphery w/ base distal | ||
| H | Hannington-Kiff sign | ? | (needed) | ||||
| H | Harrison's groove | ? | |||||
| H | Hatchcock's sign | ? | paediatrics, infectious disease | mumps | (needed) | tenderness behind angle of jaw (typically before swelling is evident) | |
| H | Heberden's node | William Heberden | rheumatology | osteoarthritis | same as bouchard's nodes, but over dip joints | ||
| H | Hegar's sign | Ernst Ludwig Alfred Hegar | obstetrics | normal pregnancy | softening of cervical isthmus appearin between 4th and 6th weeks (usually) | ||
| H | Hess test | ? | (needed) | ||||
| H | Hippocratic face | Hippocrates | palliative care | impending death | |||
| H | Hippocratic fingers | Hippocrates | pulmonary medicine | chronic hypoxia | clubbing of distal phalanges | ||
| H | Hirschberg test | Julius Hirschberg | ophthalmology | strabismus | corneal reflection centred (-) or not centred (+) on pupil | ||
| H | Hoffman's sign | Johann Hoffman | neurology | corticospinal tract lesions | tapping distal phalanx of 3rd or 4th finger elicits flexion of same in thumb | ||
| H | Hollenhorst plaque | Robert Hollenhorst | ophthalmology | hypertension, coronary artery disease, and/or diabetes | cholesterol embolus(i) of retinal artery(ies) | ||
| H | Homan's sign | John Homans | deep venous thrombosis | knee bent, ankle abruptly dorsiflexed,popliteal pain | |||
| H | Hoover's sign | Charles F. Hoover | neurology, psychiatry | lower extremety paresis | (needed) | differentiates organic from non-organic etiology | |
| H | Howship-Romberg sign | ? | (needed) | ||||
| H | Hutchinson freckle | ? | (needed) | ||||
| H | Hutchinson pupil | ? | (needed) | ||||
| H | Hutchinson's sign | ? | (needed) | ||||
| H | Hutchinson's teeth also Hutchinson's incisors | Sir Jonathan Hutchinson | pediatrics | congenital syphilis | small,widely spaced incisors,w/ notched biting surfaces | ||
| H | Hutchinson's triad | Sir Jonathan Hutchinson | [paediatrics | congenital syphilis | interstitial keratitis,nerve deafness, Hutchinson's teeth | ||
| J | Janeway lesion | Theodore Caldwell Janeway | cardiology | infective endocarditis | palmar or plantar erythematous or haemorrhagic papules | ||
| J | Jendrassik maneuver | Ernő Jendrassik | neurology | hyporeflexia | compares patellar reflex w/ and w/o distraction | ||
| J | Joffroy sign | ? | |||||
| J | John Thomas sign aka Throckmorton sign | N/A | radiology | various, including Reiter's syndrome | (needed) | penile shadow points at affected hip (+) or unaffected hip (-) (2) | |
| J | Jolly test | Friedrich Jolly | neurology | myasthenia gravis or Lambert-Eaton syndrome | (needed) | sources conflict on procedure, but agree it is to differentiate these disorders | |
| J | Jones criteria | ? | (needed) | ||||
| K | Kanavel's sign | ? | orthopedics,rheumatology | tenosynovitis of flexor digitorum tendon | http://www.emedicine.com/orthoped/TOPIC97.HTM | (1) finger held in slight flexion, (2) fusiform swelling, (3) tenderness along the flexor tendon sheath, and (4) pain with passive extension of the digit. | |
| K | Kayser-Fleischer ring | ? | neurology,gastroenterology | Wilson's disease(hepatolenticular degeneration) | ring of brownish copper deposit at corneo-scleral junction | ||
| K | Kehr's sign | Hans Kehr | trauma surgery | ruptured spleen | referred pain to L shoulder | ||
| K | Kelly's sign | Howard Atwood Kelly | surgery | (needed) | visible response of ureter when touched (means of identifying same) | ||
| K | Kerley lines | Peter Kerley | radiology | pulmonary edema | |||
| K | Kernig's sign | Woldemar Kernig | neurology | meningism,meningitis, subarachnoid haemorrhage | hip and knee fully flexed, extension of knee elicits pain and/or opisthotonus | ||
| K | Koebner's phenomenon | Heinrich Koebner | dermatology | various conditions | |||
| K | Koeppe's nodules | Leonhard Koeppe | ophthalmology | uveitis | granulomatous nodules at pupillary margin | ||
| K | Koplik's spots | Henry Koplik | pediatrics | measles | |||
| K | Korotkoff sounds | Nikolai Korotkov | cardiology | auscultatory sphygmomanometry | Korotkov described 5 sounds. Only the first (the onset of audible sound,and corresponding to systolic pressure) and the fifth (sound becomes inaudible,corresponding to diastolic pressure) are of practical clinical significance (however,see:Auscultatory gap) | ||
| K | Kussmaul breathing or respiration | Adolph Kussmaul | endocrinology | metabolic acidosis | laboured deep breathing with normal or reduced frequency | ||
| K | Kussmaul's sign | Adolph Kussmaul | cardiology | various, including right side failure | increased jugular distension on inspiration | ||
| K | Kveim test | Morten Ansgar Kveim | pulmonary medicine | sarcoidosis | intradermal injection of lymphatic extract from known sufferer; obsolete | ||
| L | Lachman maneuver | John Lachman | orthopedic surgery | anterior cruciate ligament injury | modified anterior drawer test with knee in less flexion | ||
| L | Ladin's sign | ? | obstetrics | normal pregnancy | softening of uterus; same as Hegar's sign | ||
| L | Lancisi's sign | ? | |||||
| L | Lasègue's sign | Charles Lasègue | neurosurgery, orthpaedic surgery | lumbar disc lesions, sciatica | better known as straight leg raise test | ||
| L | Leopold's maneuver | ? | obstetrics | determination of fetal lie | |||
| L | Leser-Trelat sign | ? | internal medicine | malignant neoplasm | sudden onset of multiple pruritic seborrheic keratoses | ||
| L | Levine's sign | ? | |||||
| L | Lhermitte's sign | Jean Lhermitte | neurology | ||||
| L | Lisch nodule | Karl Lisch | ophthalmology | type I neurofibromatosis | yellow brown hamartomata on iris | ||
| L | Lisker's sign | ? | internal medicine | deep venous thrombosis | tenderness on percussion of antero-medial tibia | ||
| L | Litten's sign | ? | cardiology | infective endocarditis | eMedicine | cotton-wool exudate in the retina | |
| L | Louvel's sign | ? | internal medicine | deep venous thrombosis | (needed) | valsalva (cough, sneeze)increases pain along course of suspect vein;proximal pressure prevents this | |
| L | Lowenberg's sign | ? | deep vein thrombosis | ||||
| M | MacDonald triad | John M. MacDonald | psychiatry | sociopathic personality disorder | eneuresis, firesetting and animal torture predictive of future criminal behaviour | ||
| M | Macewen's sign | Sir William Macewen | neurology, neurosurgery | hydrocephalus, brain abscess | resonance on percussion of fronto-temporo-parietal suture | ||
| M | Magnan's sign | ? | (needed) | ||||
| M | Mantoux test | Charles Mantoux | infectious disease | tuberculosis | intradermal protein derivative - diameter of wheal evaluated | ||
| M | Marcus Gunn pupil | Robert Marcus Gunn | ophthalmology, neurology | severe retinal disease, lesion of optic nerve anterior to chiasm | reduced pupillary response when light swings from affected side | ||
| M | Marie's sign | ? | (needed) | ||||
| M | Markle sign | ? | (needed) | ||||
| M | Mayne's sign | ? | (needed) | ||||
| M | McBurney's point | Charles McBurney | surgery | appendicitis | 2/3 of the way lateral on a line from umbilicus to anterior superior iliac spine (corresponds to junction of vermiform appendix and cecum) | ||
| M | McConnell's sign | ? | cardiology | pulmonary embolus | (needed) | ||
| M | McDonald's sign | ? | (needed) | ||||
| M | McMurray test | Thomas Porter McMurray | orthopaedics | meniscal tear | knee extended, valgus stress applied, leg rotated produces palpable or audible click | ||
| M | Means-Lerman scratch | ? | (needed) | ||||
| M | Mees' lines | R.A. Mees | toxicology | arsenic or heavy metal poisoning | transverse white lines across the nails | ||
| M | Mentzer index | ? | hematology | microcytic anemia | differentiates iron deficiency anaemia from beta thalassaemia | ||
| M | Miller-Fisher test | ? | (needed) | ||||
| M | Monash sign | ? | (needed) | ||||
| M | Möbius's sign | ? | (needed) | ||||
| M | Muehrckle's nails | ? | (needed) | ||||
| M | Mulder's sign | ? | (needed) | ||||
| M | Müller's maneuver | ? | |||||
| M | Müller's sign | Friedrich Müller | cardiology | aortic insufficiency | visible pulsation or bobbing of uvula | ||
| M | Murphy's punch sign | John B. Murphy | perinephric abscess | ||||
| M | Murphy's sign | John B. Murphy | surgery | cholecystitis | hesitation on inspiration while gall bladder is palpated | ||
| M | Myerson's sign | ? | neurology | Parkinson's disease | inability to resist blinking when glabella is percussed | ||
| N | Naegele's rule | Franz Karl Naegele | gynecology | gestation | method of estimating due date | ||
| N | Nardi test | George Nardi | gastroenterology | dysfunction of sphincter of Oddi | administration of morphine and neostigmine reproduces sharp LUQ pain; not in general use | ||
| N | Nikolsky's sign | ? | dermatology | various,including pemphigus vulgaris | mild shear stress applied to skin, bulla forms | ||
| O | O'Brien's test | ? | (needed) | ||||
| O | O'Donoghue's triad | D. O'Donoghue | orthopaedics, sports medicine | knee injury | coincidence of anterior cruciate injury,medial collateral injury and meniscal tear | ||
| O | Oliver's sign | William S. Oliver | cardiology | aortic arch aneurysm | caudal movement of trachea with systole | ||
| O | Oppenheim's sign | ? | (needed) | ||||
| O | Ortolani's sign | Marino Ortolani | pediatrics & orthopedics | congenital hip dislocation | /ortolanis_test_for_congenital_hip_dislocation | ||
| O | Osborn wave | J.J. Osborn | cardiology, emergency medicine | hypothermia | positive deflection at QRS-ST junction | ||
| O | Osler's node | Sir William Osler,bt. | internal medicine | various, including SBE and SLE | painful red lesions on the pads of the fingers and plantar surfaces | ||
| O | Osler's sign | Sir William Osler, 1st baronet Osler | internal medicine | atherosclerosis | falsely elevated bp reading due to incompressibility of calcified vessels | ||
| P | Palla's sign | ? | (needed) | ||||
| P | Pastia's sign | Dominic Pastia | paediatrics | scarlet fever | (needed) (Associated with Scarlatiniform rash and strep pyogenes) | lines of confluent petechiae in skin creases | |
| P | Patrick's test | ? | sacroiliitis | ||||
| P | Pemberton's sign | ? | thoracic surgery | retrosternal mass w/ superior vena cava syndrome | arms elevated over head elicits facial plethora, distended neck veins and inspiratory stridor | ||
| P | Phalen's maneuver | George Phalen | physiatry, rheumatology, hand surgery | carpal tunnel syndrome | 30-60 seconds of full forced flexion of wrist elicits symptoms | ||
| P | Piskacek's sign | ? | obstetrics | normal pregnancy | (needed) | palpable lateral bulge at tubal-uterine junction; present at 7-8 weeks | |
| P | Plummer's nail | ? | (needed) | ||||
| P | Pratt's sign | ? | internal medicine | deep venous thrombosis | (needed) | pain elicited by compression of posterior calf | |
| Q | Queckenstedt's maneuver | ? | spinal stenosis | ||||
| Q | Quincke's sign | ? | cardio;ogy | aortic insufficiency | visible pulsation in ungual capillary bed | ||
| R | Reynolds' pentad | B.M. Reynolds | gastroenterology | ascending cholangitis | Charcot's triad + hypotension and altered mental state | ||
| R | Riesman's sign | ? | (needed) | ||||
| R | Rigler's sign aka double wall sign | Leo G. Rigler | radiology, abdominal surgery | pneumoperitoneum | gas outlines both mucosal and serosal surfaces of bowel | ||
| R | Rinne test | Heinrich Rinne | ENT,neurology,audiometry | hearing loss | comparison of air conduction to bone conduction differentiates sensorineural from conductive deafness | ||
| R | Romana's sign | Cecilio Romana | tropical medicine | Chagas' disease | painless unilateral periorbital swelling | ||
| R | Romberg test | Moritz H. Romberg | neurology, other | dorsal column lesions, cerebllar lesions, etoh intoxication | differentiates proprioceptive from cerebellar ataxia | ||
| R | Rosenbach's sign | ? | (needed) | ||||
| R | Roth's spots | ? | ophthalmolgy, internal medicine | various, including SBE and systemic vasculitides | (needed) | retinal haemorrhages w/ pale centres | |
| R | Rovsing's sign | Niels Rovsing Kimpel | eneral surgery | appendicitis | palpation of LLQ elicits pain in RLQ | ||
| R | Rumpel-Leede sign | ? | (needed) | ||||
| R | Russell's sign | ? | psychiatry | bulimia nervosa, anorexia nervosa | scarring of the dorsum of one hand(contact with incisors when purging) | ||
| S | Salus's sign | ? | (needed) | ||||
| S | Schafer's maneuver | ? | (needed) | ||||
| S | Schamroth's window test | Leo Schamroth | pulmonolgy,cardiology | chronic hypoxia | identifies clubbing of distal phalanges | ||
| S | Schilling test | ? | internal medicine, gastroenteroogy | pernicious anaemia, coeliac disease, other malabsorption disorders | B12 radioassay;rare | ||
| S | Schirmer's test | ? | ophthalmology | keratoconjunctivitis sicca,as in Sjogren's syndrome | quantifies lacrimal secretion | ||
| S | Schober test | Paul Schober | physiatry, rheumatology, orthopaedics | various disorders of lumbar vertebrae | quantifies lumbar flexion | ||
| S | Shone's complex | ? | (needed) | ||||
| S | Siegrist streaks | August Siegrist | ophthalmology | malignant hypertension | hyperpigmented sreaks parallel to choroidal vessels | ||
| S | Sims-Huhner test | ? | (needed) | ||||
| S | Simmonds' test | Franklin A. Simmonds | orthopaedics | Achilles' tendon rupture | squeezing of calf fails to produce plantarflexion if A. tendon is ruptured | ||
| S | Sister Mary Joseph sign (Sister Mary Joseph nodule) | Sister Mary Joseph Dempsey (born Julia Dempsey) | oncology | various abdominal malignancies | palpable lymph node in the umbilicus | ||
| S | Spurling's test | ? | (needed) | ||||
| S | Stellwag's sign | Karl Stellwag von Carion | ophthalmology, endocrinology | thyrotoxicosis | infrequent and/or incomplete blinking, accompanied by Dalrymple's sign | ||
| S | Still's murmur | ? | paediatric cardiology | subaortic stenosis, small VSD | systolic ejection sound ;vibratory/musical;best heard at left lower sternal border | ||
| S | Stransky's sign | ? | (needed) | ||||
| S | Stroop test | John R. Stroop | neuropsychology | various, including ADHD and schizophrenia | reaction times for incongruent stimuli (e.g., word red printed in blue) | ||
| S | Strümpell's sign | Adolph Strümpell | neurology | spastic pareses of the lower extremity | (needed) | failure of abrupt passive flexion of the hip and/or knee to elicit dorsiflexion and adduction of foot | |
| T | Terry's nails | ? | internal medicine | various including hepatic failure | white 'ground glass' nails;absence of lunula | ||
| T | Tinel's sign | Jules Tinel | neurology | neuritis, compression disorders | 'DTP' - distal tingling on percussion | ||
| T | Todd's paresis | Robert Bentley Todd | neurology | seizure disorders | focal weakness for as much as 48 hours after seizure | ||
| T | Traube's sign | Ludwig Traube | various | splenomegaly | dull percussion sound over Traube's space | ||
| T | Trendelenburg's sign | Friedrich Trendelenburg | neurology,physiatry | superior gluteal palsy, other causes of hip adductors weakness | pelvic tilt contralateral to 'stance leg' | ||
| T | Trousseau's sign of malignancy | Armand Trousseau | internal medicine | various malignancies, including pancreatic | spontaneous thrombosis of multiple veins, including portal circulation | ||
| T | Trousseau's sign of latent tetany | Armand Trousseau | internal medicine,endocrinology | hypocalcaemia | in hypocalcaemia, occlusion of brachial artery induces carpal spasm | ||
| U | Uhthoff's phenomenon | Wilhelm Uhthoff | neurology | multiple sclerosis | ↑ in neurological symptoms w/ exercise | ||
| U | Unterberger test | Siegfried Unterberger | neurology, ENT | vestibular lesions | patient walks in place with eyes closed;direction of rotation indicates vestibular lesion on that side | ||
| V | Virchow's triad | Rudolf Virchow | hematology | etiology of thrombosis | |||
| V | Von Braun-Fernwalds sign | ? | (needed) | ||||
| V | Von Graefe sign | ? | endocrinology | goiter | ' lid lag'; immobility of upper lid on downward gaze | ||
| W | Wada test | Juhn A. Wada | neurology | epilepsy, anatomical lesions of cerebrum | short acting barbiturate injected in internal carotid;lateralizes language function | ||
| W | Waddell's signs | G. Waddell | primary care, psychiatry | chronic pain | identify non-organic sources of low back pain | ||
| W | Waddell's triad | ? | paediatric trauma | pedestrian stuck by motor vehicle | Head trauma, thoracic and/or abdominal trauma, femoral trauma | ||
| W | Watson's water hammer pulse | ? | cadiology | various, including aortic insufficiency | bounding forceful pulse elicitd with postural manoeuvres | ||
| W | Whipple's triad | Allen Whipple | endocrinology | hypoglycemia | 1.symptoms associated with hypoglycaemia 2. measured low serum glucose 3. relief of symptoms w/ administration of glucose p.o. or iv | ||
| W | Wickham's striae | Louis Frédéric Wickham | dermatology | lichen planus | white or greyish lines on the lichen planus lesions | ||
| W | Widal test | Georges-Fernand Widal | salmonella spp. brucella spp. | serum agglutination; obsolete(?) | |||
| W | Winterbottom's sign | ? | tropical medicine | trypanosomiasis | posterior cervical chain adenopathy | ||
| W | Wolff-Parkinson-White triad | ? | (needed) | ||||
| W | Wright's maneuver | ? | (needed) | ||||
| Yeoman's test |
(2) It is important for the reader to see the article or the external link.