Superior vena cava syndrome (SVCS), or superior vena cava obstruction (SVCO), is a result of obstruction of the superior vena cava. It is a medical emergency and requires immediate diagnosis and treatment. It most commonly occurs by direct invasion of the superior vena cava or compression of the vessel wall by right upper lobe tumours and/or mediastinal lymphadenopathy. It can also occur as a result of thrombosis in the SVC, although this is less common.
Superior vena cava syndrome usually presents more gradually with an increase in symptoms over time as malignancies increase in size or invasiveness.
Before antibiotics, untreated infections were the most common cause of SVCS. Now malignancies (in particular, lung cancer) cause most SVCS's. Common cancers that cause SVCS include bronchogenic carcinomas including small cell and non-small cell lung carcinoma, Burkitt lymphoma, lymphoblastic lymphomas, pre-T-cell lineage acute lymphoblastic leukemia (rare), and other acute leukemias.
Successful management of multiple permanent pacemaker complications - infection, 13 year old silent lead perforation and exteriorisation following failed percutaneous extraction, superior vena cava obstruction, tricuspid valve endocarditis, pulmonary embolism and prosthetic tricuspid valve thrombosis.(Case report)(Case study)
Feb 24, 2009; Authors: Pankaj Kaul (corresponding author) ; Krishna Adluri ; Kalyana Javangula ; Wasir Baig Case presentationA 40...
Focal accumulation of a radiopharmaceutical in the liver on tecnetium-99m gated pool and apcitide scintigraphy leading to the diagnosis of superior vena cava obstruction
Jan 01, 2002; Focal increased enhancement or radiopharmaceutical uptake in the liver has been associated with superior vena cava syndrome. This...