Steroid 9alpha-monooxygenase

pregna-4,9(11)-diene-3,20-dione + AH₂ + O₂ $rightleftharpoons$ 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H₂O

The 3 substrates of this enzyme are pregna-4,9(11)-diene-3,20-dione, AH2, and O₂, whereas its 3 products are 9,11alpha-epoxypregn-4-ene-3,20-dione, A, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is steroid,hydrogen-donor:oxygen oxidoreductase (9-epoxidizing). This enzyme is also called steroid 9alpha-hydroxylase. It has 2 cofactors: FMN, and Iron-sulfur.

References

• Strijewski A "The steroid-9 alpha-hydroxylation system from Nocardia species". Eur. J. Biochem. 128 125–35.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes