Sphenopsalis is a genus of extinct mammal from the Paleocene of Central Asia. It was a member of the extinct order Multituberculata, and lies within the suborder Cimolodonta and the superfamily Taeniolabidoidea. The genus was named by Matthew W.D., Granger W. and Simpson G.G. in 1928.
The one known species, Sphenopsalis nobilis, was also named by Matthew, Granger and Simpson in 1928. It was found in Upper Paleocene strata of Gashato and Nomogen of Mongolia and China. The American Museum of Natural History in New York has a specimen in its collection.