D-glucitol + NADP⁺ $rightleftharpoons$ L-sorbose + NADPH + H⁺

Thus, the two substrates of this enzyme are D-glucitol and NADP⁺, whereas its 3 products are L-sorbose, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-glucitol:NADP+ oxidoreductase. This enzyme is also called Sou1p.

References

• Greenberg JR, Price NP, Oliver RP, Sherman F, Rustchenko E "Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization". Yeast. 22 957–69.
• Rustchenko E "Erratum report: Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization". Yeast 22 1171.
• Sugisawa T, Hoshino T and Fujiwara A "Purification and properties of NADPH-linked L-sorbose reductase from Gluconobacter melanogenus N44-1". Agric. Biol. Chem. 55 2043–2049.
• Shinjoh M, Tazoe M, Hoshino T "NADPH-dependent L-sorbose reductase is responsible for L-sorbose assimilation in Gluconobacter suboxydans IFO 3291". J. Bacteriol. 184 861–3.

External links

Gene Ontology (GO) codes