"Out of Exile" is the title track from Audioslave's second album Out of Exile and the fourth and final single released in 2006. No music video was made for the song.

An excerpt of this song is being used at the 2006 Pro40 tournament.

In an interview for the bonus DVD that came with Audioslave's Revelations, Chris Cornell said that this song was written when his wife was pregnant. He said that his wife and soon-to-be-born child were a bright spot, and a way to get out of a bad mood, or "Out of Exile."