may refer to several people, objects and places:
- C. H. Sisson, British writer
- Edgar Sisson, purchaser of the Sisson Documents
- Fred Sisson, United States Representative from New York
- Jeremiah Sisson (1720-1783), British instrument maker, son of Jonathan Sisson.
- John Richard Sisson, acting President of the Ohio State University
- Jonathan Sisson (1690-1749), British instrument maker.
- Sisson Documents, forged Russian documents which purported that Trotsky and Lenin were agents in the pay of the German government
- Sisson, California, now Mount Shasta City, named after prominent land owner Justin Sisson