Shu may refer to:
- Shu (Egyptian deity)
- 蜀 (Shǔ), an abbreviation of Sichuan province of the People's Republic of China, as well as the following historical regimes that existed in this region:
- Shu (state), a state during the Zhou Dynasty era
- Shu Han, a kingdom during the Three Kingdoms Period
- Former Shu, a kingdom during the Five Dynasties and Ten Kingdoms Period
- Later Shu, another kingdom during the Five Dynasties and Ten Kingdoms Period
- The Kazakh name for the Chui River
- Shu, Kazakhstan
Shu is the name of:
SHU may be an acronym for:
- Seton Hall University, in South Orange, New Jersey
- Sacred Heart University, in Fairfield, Connecticut
- Scoville Heat Unit, a measurement of hotness or spiciness in food
- Security Housing Unit, a solitary confinement space in a maximum security Prison
- Seton Hill University, in Greensburg, Pennsylvania
- Shanghai University (上海大学), in Shanghai, China
- Shih Hsin University (世新大學), in Taipei, Taiwan
- Sheffield Hallam University, a modern university in Northern England
- Special Handling Unit, a super maximum security prison located in Sainte-Anne-des-Plaines, Quebec