Bacterial disease caused by a toxin produced by the bacterium Staphylococcus aureus. It was first recognized in 1978 in women using superabsorbent tampons. High fever, diarrhea, vomiting, and rash may progress to abdominal tenderness, drop in blood pressure, shock, respiratory distress, and kidney failure. The syndrome also has other causes, including postsurgical infection. Antibiotics are not effective. With intensive supportive therapy, most patients recover in 7–10 days, but 10–15percnt die. Many patients have a milder recurrence within eight months.
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Method of treating psychiatric disorders by inducing shock through electric current. Electroconvulsive, or electroshock, therapy involves passing an electric current through the patient's head between two electrodes placed over the temples and thus causing a convulsive seizure; it was used to treat bipolar disorder and other types of depression. Shock was previously induced by administering increasingly large doses of insulin until the patient was thrown into a brief coma; the so-called insulin-shock therapy was used for the treatment of schizophrenia. Both forms of shock therapy were developed in the 1930s. Their use declined after the introduction of tranquilizing drugs and antidepressants.
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Device for controlling unwanted motion of a spring-mounted vehicle. On an automobile, the springs act as a cushion between the axles and the body and reduce the shocks produced by a rough road surface. Since some combinations of road surface and car speed may result in excessive up-and-down motion of the car body, shock absorbers—which today are hydraulic devices that oppose both compression and stretching of the springs—slow down and reduce the magnitude of these vibratory motions. Seealso damping.
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State in which the circulatory system fails to supply enough blood to peripheral tissues to meet basic requirements. Symptoms—weak, rapid pulse; low blood pressure; and cold, sweaty skin—are not all present in every case. Causes include low blood volume, caused by bleeding or fluid loss from burns or dehydration; inability of the heart to pump enough blood, due to heart attack, pulmonary embolism, or cardiac tamponade (compression of the heart by fluid in the membrane around it); and blood-vessel dilation as a result of septicemia, allergy (including anaphylaxis), or drugs. All result in reduced capillary blood flow; reflexes increase heart rate and constrict small blood vessels to protect the blood supply to essential organs. Without treatment of the underlying cause, these mechanisms fail; since the cause is not always clear, cases tend to require different and occasionally contradictory treatment (e.g., intravenous fluids can save the life of a patient with massive blood loss but can overload a weakened heart).
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Physical effect of an electric current that enters the body, ranging from a minor static-electricity discharge to a power-line accident or lightning strike but most often resulting from house current. The effects depend on the current (not the voltage), and the worst damage occurs along its path from the entry to the exit point. Causes of immediate death are ventricular fibrillation and paralysis of the brain's breathing centre or of the heart. Cardiopulmonary resuscitation is the best first aid. Though most survivors recover completely, aftereffects may include cataract, angina pectoris, or nervous-system disorders.
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Severe, immediate, potentially fatal bodily reaction to contact with a substance (antigen) to which the individual has previously been exposed. Often triggered by antiserum, antibiotics, or insect stings, the reaction's symptoms include skin flushing, bronchial swelling (with difficulty breathing), and loss of consciousness. Shock may follow. Milder cases may involve hives and severe headache. Treatment, consisting of injection of epinephrine, followed by antihistamines, cortisone, or similar drugs, must begin within minutes. Anaphylaxis may be caused by extremely small amounts of antigen.
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