L-serine + NADP⁺ $rightleftharpoons$ 2-ammoniomalonate semialdehyde + NADPH + H⁺

Thus, the two substrates of this enzyme are L-serine and NADP⁺, whereas its 3 products are 2-ammoniomalonate semialdehyde, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-serine:NADP+ 3-oxidoreductase.

References

• Fujisawa H, Nagata S, Chowdhury EK, Matsumoto M, Misono H "Cloning and sequencing of the serine dehydrogenase gene from Agrobacterium tumefaciens". Biosci. Biotechnol. Biochem. 66 1137–9.
• Chowdhury EK, Higuchi K, Nagata S, Misono H "A novel NADP(+)-dependent serine dehydrogenase from Agrobacterium tumefaciens". Biosci. Biotechnol. Biochem. 61 152–7.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes