Sane is an English word meaning "of sound mind"; see Sanity.

Sane may also refer to:

• Sane (Chalcidice) Ancient Greek city
• SANE (charity), a mental health charity in the UK
• SANE, the Committee for a SANE Nuclear Policy (now part of Peace Action)
• Scanner Access Now Easy (SANE), a scanner software interface for most Unix and Unix-like systems
• An archaeological site and a modern name of Sani, Greece
• Sexual Assault Nurse Examiner, a nurse who performs a medical-forensic examination of victims of sexual assault
• Sane Guruji Indian Author and Social Reformer