Buck was born in Dallas but raised in Washington, D.C.
Buck played Det. G. Lynn Bishop in Law & Order: Criminal Intent, temporarily replacing Det. Alexandra Eames (played by Kathryn Erbe) while the latter was on maternity leave. Buck's television roles have not been limited to only drama; she also played a character on the comedy series Stella. She recently wrapped her directorial debut, 21 BELOW, a documentary that takes an in-depth look at a family from Buffalo, NY. It reveals their economic, social, interpersonal struggles, and their fight to stay together while their world around them pulls them apart.
When she was younger, Samantha Buck worked as a VJ for MTV.