Robert Geoffrey Edwards, CBE (born 27 September 1925, Leeds) is a British physiologist and pioneer in reproductive medicine, and in-vitro fertilization in particular.
Early career
After finishing Manchester Central High School, he served in the British Army, and then completed his undergraduate studies in agriculture at the
University of Wales, Bangor. Subsequently he studied at the Institute of Animal Genetics,
University of Edinburgh. He received his Ph.D. in 1955. In 1963 he joined the
University of Cambridge.
Human Fertilization
About 1960 Edwards had started to study human
fertilization, and he continued his work at Cambridge laying the groundwork for his later success. In 1968 he was able to achieve fertilization of the human egg in the laboratory and started to collaborate with
Patrick Steptoe, a gynecologic surgeon from
Oldham. Edwards developed human culture media to allow the fertilization and early
embryo culture, while Steptoe utilized
laparoscopy to recover
ovocytes from patients with tubal
infertility. Their attempts met significant hostility and opposition.
1978
The birth of
Louise Brown at 11:47 p.m. on
25 July 1978 at the
Oldham General Hospital made medical history: with
in vitro fertilization being successful, a new way had been opened to help infertile couples who had formerly no chance of having a baby.
Consequences
Refinements in technology have increased pregnancy rates and it is estimated that in 2004 about 1.5 million children have been born by IVF.
Their breakthrough laid the groundwork for further innovations such as intracytoplasmatic sperm injection ICSI, embryo biopsy (PGD), and stem cell research. Edwards and Steptoe founded the Bourn Hall Clinic as a place to advance their work and train new specialists. Steptoe died in 1988. Edwards has continued a productive career as a scientist and editor of noted medical journals.
See also
References
- Steptoe, P. C., and Edwards, R. G. (1978) Birth after the reimplantation of a human embryo. Lancet. 2: 366.