D-ribose + NADP⁺ + H₂O $rightleftharpoons$ D-ribonate + NADPH + H⁺

The three substrates of this enzyme are D-ribose, NADP⁺, and H₂O, whereas its 3 products are D-ribonate, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-ribose:NADP+ 1-oxidoreductase. Other names in common use include D-ribose dehydrogenase (NADP+), NADP+-pentose-dehydrogenase, and ribose 1-dehydrogenase (NADP+).

References

• Scher BM, Horecker BL "Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis". Arch. Biochem. Biophys. 116 117–28.
• Schiwara HW, Domschke W, Domagk GF "[Sugar dehydrogenases in mammalian liver. I. Differentiation of various sugar dehydrogenases from pig liver by disc electrophoresis and ion exchange chromatography]". Hoppe. Seylers. Z. Physiol. Chem. 349 1575–81.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes