Brooke drives 2 Aquarius Blue Volkswagen New Beetle Convertibles on the show- a 2003 (Seasons 1-3) and a 2006 (Season 4). Both are shown a lot throughout the four seasons. Also, in 3x14, the rental car she is driving to NY with Peyton and Haley is a Majestic Amethyst 2006 Chevrolet HHR. Brooke's Season 5 car is a Platinum Bronze 2008 BMW X5 4.8i (shown a lot in 5x15 and briefly in 5x13 as well).
She takes a liking to Lucas Scott (Chad Michael Murray), and starts hitting on him in her usual way. Lucas takes it in his stride, and does not feel that Brooke wants to be in a relationship with him. One night, after Peyton is drugged at a party, Brooke calls Lucas for help. And while caring for a drugged-out Peyton, Lucas sees a whole new side of Brooke; he realizes that she may seem judgemental and unkind, but there is a whole different side to Brooke Davis. A side where she is compassionate and understanding. That night, Lucas and Brooke form a strong bond and eventually start dating. But halfway into the new relationship, Lucas realizes that his feelings for Peyton are too strong to be ignored anymore, and vice versa and the two start a secret affair. However, Brooke soon finds out, much to her anger and heartbreak. Furious and betrayed, Brooke ends her relationships with both of them; Peyton feeling guilty about betraying her best friend breaks up with Lucas; however this does nothing to soothe Brooke who feels that she was totally and utterly betrayed by Peyton. Brooke later said to Peyton before the prom; “You don't get it, do you?” It's not even about Lucas, it's about you'. Brooke and Lucas also had a pregnancy scare following their break up. Lucas said he would be there for her but she rejected him. During an argument she receives the results. She then lies and pretends to be pregnant when it turns out she isn't to punish him for cheating on her with her best friend, Peyton. Later she tells Peyton that she was lying, and in doing so, achieves her goal because Peyton is as pleased as she is that they can continue their relationship. Towards the end of the season, when Lucas also hurt Peyton by hooking up with Nicki, a woman (who he had met at a bar) who turned out to be Jake Jagielski's ex and Jenny's mother, Brooke decided to try and make things better with Peyton. She approached her at the beach party and said; “I love you P.Sawyer”, before Peyton replied, “I love you too, B.Davis”.
Brooke then decides to run for Student Council President, against students who are much more studious, hard working and experienced than her. Brooke doesn't back down even in the face of dirty politics by one Erica Marsh (Katherine Bailess), and wins the post of Student Council President after Mouth delivers a touching recommendation speech to a packed auditorium for her. She quickly befriends Mouth once again, as well as Erica, who she feels sorry for, as Erica it turns out doesn't have any friends. Then, Brooke finds out that her parents are moving to California as her father has got a new job. Brooke is shocked when she finds out the surprise Lucas has in store for her: Karen has convinced Brooke's parents to let her stay with her, in Lucas' room, until the summer, since Lucas is living with Dan. Not only that, but Lucas has already arranged all her stuff in his room. Brooke also finds out that it was Felix who spray-painted the word 'DYKE' on Peyton's locker and immediately breaks up with him. Peyton fights back though, by writing 'DYKE' on her t-shirt to show everyone she can handle it and is told to remove the shirt at once by the principal. Felix is also kicked out of Tree Hill High as a result of his actions and his family sends him to military school. At last, summer arrives, and as Brooke is about to leave for California, Lucas finally confesses his true feelings to her.
As the 3rd Season begins, Brooke realizes that deep down; she has had feelings for Lucas since she first met him. But, she still remembers how ugly things turned and is afraid of getting hurt again. She decides that they can date, but non-exclusively. However, there's a small problem: Lucas refuses to date other girls. So Brooke introduces a 'Fantasy Boy Draft' and accidentally sets him up with Rachel Gatina (Danneel Harris), a new cheerleader whom she's jealous of. The two butt heads and fight for the affections of Lucas, even getting into a catfight while cheerleading. But despite Rachel's attempts, Lucas turns her down and says that he still loves Brooke. Brooke, however, thinking that she may have lost her opportunity to be with Lucas, gets drunk and sleeps with Chris Keller, worse still, Lucas walks in on them. Realizing that if she had just come out with her feelings and told Lucas that she loves him then everything would have been fine. So she gives him the 82 letters that she had written to him but didn't send. Lucas forgives her and they get together.
She also develops a clothing line Clothes Over Bros, and also makes Haley's wedding dress. However when Peyton reveals to Brooke that she has feelings for Lucas, bringing back the 'triangle', Brooke is enraged once again, and promptly ends her friendship with a teary-eyed Peyton. At the wedding things have not lightened up and it is clear for everyone to see and especially Lucas, that Brooke is very upset, especially with Peyton. Brooke tells him to not hang around or speak to Peyton. When Lucas and Brooke are dancing together Lucas lets slip that he and Peyton kissed during the shootout, this hurts Brooke even more and she leaves him.
Rachel then pretends to need Haley's tutoring so that they can steal the answers to a Calculus test for Brooke who is failing it but they get caught and pretend to have joined the Clean Teens as an alibi. There she meets Chase Adams (Stephen Coletti), a virtuous and attractive Clean Teen, who had also been betrayed by his lover and best friend and they tip-toe back in the world of loving. During a class assignment, Brooke reveals to Chase that she cheated on the Calculus test.She also says she thinks she isn't pretty enough or talented enough for him, due to her relationship with Lucas. He tells her that she is good enough, and all she needs to do is to stop lying and be herself. They kiss and begin a new relationship together. The next week Chase and Brooke attend an event at Nathan's house. Sadly, it is on this occasion that Brooke's promiscuity comes to light once again. A tape entitled "Nathan Scores" was to show game footage but instead cuts to Brooke and Nathan having drunken sex. After the tape is turned off, Brooke quickly starts to apologize to Peyton, but is quickly cut off of as Peyton punches her in the face causing her to have a black eye on prom. Because of the tape, a lot of people are mad at Brooke. First is of course Haley. She wished Brooke had told her about the tape earlier. Next is Peyton. She is angry that Brooke completely cut her out of her life for being honest about her feelings when she felt Brooke was never honest with her. She tells Brooke how much it hurt her when Brooke made fun of her mom’s death. Peyton told Brooke that she was dead to her. In the end, Peyton takes a black light marker and writes "whore" on Brooke's dress. Brooke interprets that as Peyton still caring about her. After hearing from Lucas that Peyton isn't going to prom, she suspects something is up and goes over to her house. Her front door is locked, so she's goes to the back knowing there is a hide-a-key. Derek spots her, and as Brooke makes her way down Peytons' basement steps in time to see Peyton tied up, he has his hand to her throat, and she's tied up next. When Peyton asks what she's doing here she replies that they've been talking about senior prom since they were 8, she knew something was wrong if Peyton wasn't going. Peyton manages to convince Derek to let her kill Brooke, but instead stabs him. Untied, Peyton tries to untie Brooke, but as Derek starts to move and get up, Brooke tells Peyton to run, which she does. In her room, Peyton starts to punch and kick Derek, punishing him for everything he's done, but he overpowers her and as he is about to rape her, Brooke shows up and hits him with an axe. They continue to fight onto the stairs, until Brooke kneels down on all fours and says to Peyton, "8th grade cheer camp." Peyton kicks Derek so he falls over Brooke down stairs. They both walk down to see his body, Brooke carefully stating that they always jump up. He does, but Peyton kicks him. They rekindle their friendship with Brooke saying, "I guess it's hoes over psychos now." They go to prom together where Brooke is elected Prom Queen.
The next day at school, Brooke meets Chase again, and he says that he kept trying to call her after she was tied up by Ian Banks. Brooke ignored Chase. After receiving a cryptic message from Mouth, the entire gang consisting of Brooke, Haley, Lucas, Skills, Nathan, and Peyton set out on a cross country road trip to Honey Grove, Texas to save him. Upon returning from her road trip, Brooke and Chase get back together. Now that Brooke and Chase are dating again, they have sex at the graduation party. She becomes the godmother to Haley and Nathan's newborn son, James Lucas Scott. Brooke and Lucas exchange deep confessions and remend their friendship. Brooke and Peyton prepare to spend the summer in LA, with her parents.
Brooke and Victoria "bond" over the store opening, but she is oblivious that Victoria is running around insulting all of her friends. The store's opening is both a social success and a commercial failure, leading her mother to tear her down. She then reaches the breaking point after her mother attacks Peyton and rejects her daughterly love confession, beginning to rule her company her way and refusing to consider Victoria her mother any longer.. Brooke considers dating Owen, a bartender, and sets Mouth up on a blind date with Milicent. She also tells Peyton to go after Lucas because they are meant to be and comforts her after she finds out he proposed to Lindsey. She uses her naked-in-the-back-of-the-car trick on Owen and successfully gets his attention but then refuses to sleep with him. Brooke then slowly becomes friends with Lindsey but after they get stuck in the library with Haley, Peyton and Mia, Peyton tells her that she's her best friend and will always be, stopping the awkwardness. She travels to New York with Owen after she challenges him since he thinks she does nothing for her job. She shows him a space she bought to expand and they find Rachel, overdosed on drugs. Feeling guilty for firing her earlier, Brooke takes Rachel back to Tree Hill with her so she can live in Brooke's big house with her and Peyton. She attends Lucas and Lindsey's joint bachelor/bachelorette party with Owen, who brings along a surprise guest Chase, whom she had unknowingly set Peyton with up. She finally fires Victoria from the company after she scares Rachel off for monetary purposes. She tells Peyton and Lucas that she came back to Tree Hill to have a baby, because there was a void in her heart only having a family could fill. Due to this decision Brooke gets interviewed by a woman from an adoption agency who Brooke finds out has spoken to Victoria. Because of her young age, busy life and party past, Brooke is turned down. Owen then immediately ends his potential relationship with Brooke, after finding out she wants a baby, calling her selfish. However, she gets to have a baby, as she gains momentary custody of Angie who is there to get her heart operated on and finds it immediately challenging, but finds comfort and help in the form of Peyton and a now closer Lucas Brooke is terrified and distraught over the possibility of Angie not making it through her surgery, but Angie comes out perfectly and everything in Brooke's world calms down. She then has to return Angie early making her distraught but once again closer to Lucas. It appears that Brooke's feelings towards Lucas are resurfacing. In the season finale, Lucas calls someone asking that someone if she wants to get married at Las Vegas - the someone could be Lindsey, Peyton or Brooke (it turns out he called Peyton).
The initial Clothes Over Bros line features styles from casual to dressy. It was an immediate hit with her customers, selling past their expectations on the website (which, in actuality, is also a valid retailer for One Tree Hill fans interested in purchasing the designs). Clothing lines success grew, putting Brooke in a difficult position of choosing between showcasing her designs at a New York Fashion Show and starting her career, or leading her Tree Hill Cheerleaders to their final competition. In the end, Brooke chose the latter once she realized that she was not yet ready to enter the fast-paced world of Fashion and was more than happy to finish off her Senior Year with her friends. During an interview with the school's counselor, Brooke voices her intentions of studying Fashion Design after High School.
Clothes Over Bros continues to be recognized in Season 4, with Brooke's designs appearing in local fashion shows. When Brooke is involved in a cheating scandal, she's forced to keep from turning herself in to administration in order to maintain an offer to sell her clothing line by Victoria's Secret. She eventually does turn herself in to the principal, but does not get into trouble.
In season 5, Clothes Over Bros has become a full blown fashion company headed by Brooke Davis herself but with the business side carried out by her mother Victoria. The Clothes Over Bros dynasty consists of B. Davis magazine and a high end Couture line.
The Clothes Over Bros logo (C|B) is incorporated on Peyton's drawing of a heart on fire. The label's name itself is based on the saying between Brooke and Peyton, "Hoes Over Bros".
Brooke admits in 'I Forgot To Remember To Forget' she started her company 'Clothes Over Bros' to deal with her broken heart after her break up with Lucas.