See his Correspondence, ed. by E. Lankester (1848) and Further Correspondence, ed. by R. W. Gunther (1928); C. E. Raven, John Ray, Naturalist (2d ed. 1951).
See his autobiography (1963). See also studies by N. Baldwin (1988), M. Foresta (1988), and R. Penrose (1989); Man Ray Fautographe (CD-ROM, 1996).
Ray's recurrent themes—the life of Bengal's various social classes, the conflict of old and new values, and the effects of India's rapidly changing economic and political conditions—are evident throughout his oeuvre. His more than 30 films include The Music Room (1958), Charulata (1964), The Target (1972), Distant Thunder (1973), The Home and the World (1984), The Visitor (1991), and The Stranger (1992). Over the years, he received many prizes, including an Academy Award for lifetime achievement (1992). Ray was also a screenwriter, wrote the musical scores for many of his films, and was intimately involved with all the elements of their production.
See his essays, Our Films, Their Films (1995); M. Seton, Portrait of a Director: Satyajit Ray (1971); S. Benegal, Benegal on Ray (1988); B. Nyce, Satyajit Ray: A Study of His Films (1988); A. Robinson, Satyajit Ray: The Inner Eye (1989); B. Sarkar, The World of Satyajit Ray (1992); and N. Ghosh, Satyajit Ray at 70 (1993).
The rays, which form the order Batoidea, are divided into seven families. The largest are the mantas, also called devil rays and devilfish (family Mobulidae). These are top-swimming forms which may weigh up to 3,000 lb (1360 kg), with a width of up to 22 ft (7 m). Unlike most rays, mantas are filter-feeders; the manta uses a pair of horns at the front of the head to drive small prey into its mouth; there the prey is caught in a strainer and swallowed, the water passing out through the manta's gills. Electric rays, or torpedos (family Torpedinidae), have electric organs in their wings that generate electric current, used to immobilize prey and for defense. The current is strong enough to stun humans, and it is said that the ancient Greeks used these fish for shock therapy. Skates (family Rajidae), which are sometimes caught for food, are bottom dwellers; some species have electric organs in their tails. The stingrays, or whiprays (family Dasyatidae), have rows of spines along their tails, which are generally much longer than their bodies. The stingray inflicts wounds by lashing with its tail; the spines contain a poison that causes pain and can be fatal to humans. Most of the eagle rays and bat rays (family Mylobatidae) bear a single poison spine on the tail. The guitarfishes (family Rhinobatidae) are sharklike in form, having well-developed tails used for swimming and smaller pectoral fins than most rays; however, the fins are attached, as in all rays, above the gills, giving these fishes a broad-headed appearance. Sawfishes (family Pristidae) are similar in body form, but have long, flat snouts with a row of toothlike projections on either side. Some species reach a total length of 20 ft (6 m), with snouts 6 ft (1.8 m) long and 1 ft (30 cm) wide. They use these ponderous weapons to slash and impale small fishes and to probe in the mud for burrowing animals. Sawfishes, which are endangered globally, should not be confused with saw sharks, which are true sharks.
Fertilization is internal in rays. Most bear live young, but the skates lay flattened, rectangular eggs, enclosed in leathery shells, with tendrils at the corners for anchorage. Empty egg cases of this type are found on beaches and are known as mermaids' purses. Most ray families have a more or less cosmopolitan distribution in tropical and subtropical marine waters; some include temperate or cold-water species. Some rays can live in brackish bays and estuaries, and the sawfish enters freshwater rivers and lakes.
Rays are classified in the phylum Chordata, subphylum Vertebrata, class Chondrichthyes, subclass Elasmobranchii, order Batoidea.
See his autobiography (1978); biographies by D. Ritz (1978) and M. Lydon (1999).
See biographies by W. L. Johnson (1980), D. Mogen (1986), and S. Weller (2005); studies by G. E. Slusser (1977), W. F. Touponce (1989 and 1998), J. Anderson (1990), and R. A. Reid (2000).
See his Grinding It Out: The Making of McDonald's (1977, repr. 1990).
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Cow-nosed ray (Rhinoptera bonasus), a stingray
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Any of several genera of warm-water marine rays, constituting the family Mobulidae, that are wider than they are long. Extensions of the pectoral fins project from the front of the head, looking like devils' horns; these sweep plankton and small fishes into their mouths. The long, whiplike tail may have one or more stinging spines. Mantas swim near the surface by flapping their pectoral fins. The largest species, the powerful but inoffensive Atlantic manta, or giant devil, ray (Manta birostris), may grow to over 23 ft (7 m) wide; contrary to old tales, it does not envelop and eat divers.
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Penetrating very short-wavelength electromagnetic radiation, similar to an X-ray but of higher energy, that is emitted spontaneously by some radioactive substances (see gamma decay; radioactivity). Gamma radiation also originates in the decay of certain subatomic particles and in particle-antiparticle annihilation (seealso antimatter). Gamma rays can initiate nuclear fission, can be absorbed by ejection of an electron (see photoelectric effect), and can be scattered by free electrons (see Compton effect).
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Electric ray (Narcine brasiliensis)
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High-speed particle (atomic nucleus or electron) that travels through the Milky Way Galaxy. Some cosmic rays originate from the Sun, but most come from outside the solar system. Primary cosmic rays that reach Earth's atmosphere collide with nuclei in it, creating secondaries. Because lower-energy primaries are strongly influenced by the interplanetary magnetic field and Earth's magnetic field (see geomagnetic field), most of those detected near Earth have very high energy, corresponding to speeds about 87percnt that of light or more. Observations from spacecraft indicate that most cosmic rays come from the Galaxy's disk, but the highest-energy ones are probably extragalactic. Details of their production and acceleration remain unclear, but apparently expanding shock waves from supernovas can accelerate particles. From the early 1930s to the 1950s, cosmic rays were the only source of high-energy particles used in studying the atomic nucleus and its components. Short-lived subatomic particles were discovered through cosmic-ray collisions, leading to the rise of particle physics. Even powerful particle accelerators cannot impart energy anywhere near that of the highest-energy cosmic rays. Seealso Victor Francis Hess.
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Electronic display device used to produce patterns on a screen that are the graphical representations of electrical signals. Time is normally on the horizontal axis, and a function of the voltage generated by the input signal to the oscilloscope on the vertical axis; four or more plots can be simultaneously shown. Because almost any physical phenomenon can be converted into a corresponding electric voltage, oscilloscopes find commercial, engineering, and scientific applications in acoustic research, television-production engineering, and electronics design.
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Stream of electrons leaving the negative electrode, or cathode, in an evacuated or gas-filled discharge tube or emitted by a heated filament in certain electron tubes. Cathode rays cause fluorescent materials to luminesce and are utilized in cathode-ray oscilloscopes and television tubes (see cathode-ray tube).
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(born May 3, 1921, Detroit, Mich., U.S.—died April 12, 1989, Culver City, Calif.) U.S. boxer. Robinson began boxing in high school in New York City and won all of his 89 amateur fights. He was six times a world champion, once (1946–51) as a welterweight (147 lbs) and five times (1951–60) as a middleweight (160 lbs). In 201 professional bouts, he made 109 knockouts. He suffered only 19 defeats, most when he was past 40. His outstanding ability and flamboyant personality made him a hero of boxing fans throughout the world, and he is sometimes considered the best fighter in history.
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Satyajit Ray.
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(born May 3, 1921, Detroit, Mich., U.S.—died April 12, 1989, Culver City, Calif.) U.S. boxer. Robinson began boxing in high school in New York City and won all of his 89 amateur fights. He was six times a world champion, once (1946–51) as a welterweight (147 lbs) and five times (1951–60) as a middleweight (160 lbs). In 201 professional bouts, he made 109 knockouts. He suffered only 19 defeats, most when he was past 40. His outstanding ability and flamboyant personality made him a hero of boxing fans throughout the world, and he is sometimes considered the best fighter in history.
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Satyajit Ray.
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(born Aug. 25, 1890, Philadelphia, Pa., U.S.—died Nov. 18, 1976, Paris, France) U.S. photographer, painter, and filmmaker. He grew up in New York City, where he studied architecture, engineering, and art. With Marcel Duchamp he formed the New York Dada group in 1917 and produced ready-mades. In 1921 he moved to Paris and became associated with the Surrealists. He rediscovered the technique for making “cameraless” pictures (photograms), which he called “rayographs,” by placing objects on light-sensitive paper; he also experimented with the technique of solarization, which renders part of the image negative and part positive by exposing a print or negative to a flash of light during development. He turned to portrait and fashion photography and made a virtually complete record of the celebrities of Parisian cultural life of the 1920s and '30s. He also made important contributions as an avant-garde filmmaker in the 1920s.
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(born Nov. 29, 1627, Black Notley, Essex, Eng.—died Jan. 17, 1705, Black Notley) British naturalist and botanist. He attended Cambridge University and spent many years there as a fellow. With Francis Willughby (1635–1672) he undertook a complete catalog of living things, of which he published numerous volumes. His enduring legacy to botany was the establishment of species as the ultimate unit of taxonomy. He attempted to base his systems of classification on all the structural characteristics of organisms, including internal anatomy, rather than on a single feature. By insisting on the importance of lungs and heart structure, he effectively established the class of mammals, and he divided insects according to the presence or absence of multiple metamorphoses. Coming closer to a truly natural system of taxonomy than had any of his contemporaries, Ray helped make possible Carolus Linnaeus's later contributions.
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Ray Kroc
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(born Aug. 22, 1920, Waukegan, Ill., U.S.) U.S. author. Bradbury is best known for highly imaginative science-fiction stories and novels that blend social criticism with an awareness of the hazards of runaway technology. The Martian Chronicles (1950; television miniseries, 1980) is considered a science-fiction classic. His other short-story collections include The Illustrated Man (1951; film, 1969), The October Country (1955), I Sing the Body Electric! (1969; teleplay, 1981), and Quicker Than the Eye (1996). Among his novels are Fahrenheit 451 (1953; film, 1966); Dandelion Wine (1957; film, 1997) and its sequel, Farewell Summer (2006); and Death Is a Lonely Business (1985).
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(born Sept. 23, 1930, Albany, Ga., U.S.—died June 10, 2004, Beverly Hills, Calif.) U.S. pianist, singer, and songwriter. His family moved to Greenville, Fla., where he began his musical career at age 5 in a neighbourhood café. By age 7 he had completely lost his sight. He learned to write scores in Braille. Orphaned at 15, he left school to play professionally. He recorded “Mess Around” and “It Should've Been Me” in 1952–53, and his arrangement for Guitar Slim's “The Things That I Used to Do” became a million-seller. Combining blues and gospel music influences, a distinctive raspy voice, and liquid phrasing, Charles later had hits with “What'd I Say,” “Georgia on My Mind,” and “Hit the Road, Jack.” His Modern Sounds in Country and Western Music (1962), marking unusual territory for a black performer, sold more than a million copies. He received 13 Grammy Awards, including a lifetime achievement award in 1987. Charles was inducted into the Rock and Roll Hall of Fame in 1986.
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(born Aug. 22, 1920, Waukegan, Ill., U.S.) U.S. author. Bradbury is best known for highly imaginative science-fiction stories and novels that blend social criticism with an awareness of the hazards of runaway technology. The Martian Chronicles (1950; television miniseries, 1980) is considered a science-fiction classic. His other short-story collections include The Illustrated Man (1951; film, 1969), The October Country (1955), I Sing the Body Electric! (1969; teleplay, 1981), and Quicker Than the Eye (1996). Among his novels are Fahrenheit 451 (1953; film, 1966); Dandelion Wine (1957; film, 1997) and its sequel, Farewell Summer (2006); and Death Is a Lonely Business (1985).
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(born Nov. 29, 1627, Black Notley, Essex, Eng.—died Jan. 17, 1705, Black Notley) British naturalist and botanist. He attended Cambridge University and spent many years there as a fellow. With Francis Willughby (1635–1672) he undertook a complete catalog of living things, of which he published numerous volumes. His enduring legacy to botany was the establishment of species as the ultimate unit of taxonomy. He attempted to base his systems of classification on all the structural characteristics of organisms, including internal anatomy, rather than on a single feature. By insisting on the importance of lungs and heart structure, he effectively established the class of mammals, and he divided insects according to the presence or absence of multiple metamorphoses. Coming closer to a truly natural system of taxonomy than had any of his contemporaries, Ray helped make possible Carolus Linnaeus's later contributions.
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(born Sept. 23, 1930, Albany, Ga., U.S.—died June 10, 2004, Beverly Hills, Calif.) U.S. pianist, singer, and songwriter. His family moved to Greenville, Fla., where he began his musical career at age 5 in a neighbourhood café. By age 7 he had completely lost his sight. He learned to write scores in Braille. Orphaned at 15, he left school to play professionally. He recorded “Mess Around” and “It Should've Been Me” in 1952–53, and his arrangement for Guitar Slim's “The Things That I Used to Do” became a million-seller. Combining blues and gospel music influences, a distinctive raspy voice, and liquid phrasing, Charles later had hits with “What'd I Say,” “Georgia on My Mind,” and “Hit the Road, Jack.” His Modern Sounds in Country and Western Music (1962), marking unusual territory for a black performer, sold more than a million copies. He received 13 Grammy Awards, including a lifetime achievement award in 1987. Charles was inducted into the Rock and Roll Hall of Fame in 1986.
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X-radiation (composed of X-rays) is a form of electromagnetic radiation. X-rays have a wavelength in the range of 10 to 0.01 nanometers, corresponding to frequencies in the range 30 petahertz to 30 exahertz (30×1015Hz to 30×1018Hz) and energies in the range 120 eV to 120 keV. They are longer than gamma rays but shorter than UV rays. In many languages, X-radiation is called Röntgen radiation after one of its first investigators, Wilhelm Conrad Röntgen.
X-rays are primarily used for diagnostic radiography and crystallography. As a result, the term "X-ray" is metonymically used to refer to a radiographic image produced using this method, in addition to the method itself. X-rays are a form of ionizing radiation and as such can be dangerous.
X-rays span 3 decades in wavelength, frequency and energy. From about 0.12 to 12 keV they are classified as soft x-rays, and from about 12 to 120 keV as hard X-rays, due to their penetrating abilities.
The rem is the traditional unit of dose equivalent. This describes the energy delivered by - or X-radiation (indirectly ionizing radiation) for humans. The SI counterpart is the sievert (Sv). One sievert is equal to 100 rem. Because the rem is a relatively large unit, typical equivalent dose is measured in millirem (mrem) - 1/1000 rem, or in microsievert (μSv) - 1/1000000 Sv -, whereby 1 mrem equals 10 μSv.
The average person living in the United States is exposed to approximately 150 mrem annually from background sources alone.
Reported dosage due to dental X-rays seems to vary significantly. Depending on the source, a typical dental X-ray of a human results in an exposure of perhaps, 3, 40, 300, or as many as 900 mrems (30 to 9,000 μSv).
| Target | Kβ₁ | Kβ₂ | Kα₁ | Kα₂ |
|---|---|---|---|---|
| Fe | 0.17566 | 0.17442 | 0.193604 | 0.193998 |
| Co | ||||
| Ni | 0.15001 | 0.14886 | 0.165791 | 0.166175 |
| Cu | 0.139222 | 0.138109 | 0.154056 | 0.154439 |
| Zr | 0.070173 | 0.068993 | 0.078593 | 0.079015 |
| Mo | 0.063229 | 0.062099 | 0.070930 | 0.071359 |
| W | ||||
| Re |
The basic production of X-rays is by accelerating electrons in order to collide with a metal target. (In medical applications, this is usually tungsten or a more crack-resistant alloy of rhenium (5%) and tungsten (95%), but sometimes molybdenum for more specialized applications, such as when soft X-rays are needed as in mammography. In crystallography, a copper target is most common, with cobalt often being used when fluorescence from iron content in the sample might otherwise present a problem. )
In the X-ray tube the electrons suddenly decelerate upon colliding with the metal target and if the electron has enough energy it can knock out an electron from the inner shell of the metal atom and as a result electrons from higher energy levels then fill up the vacancy and X-ray photons are emitted. This process is extremely inefficient (~0.1%) and thus to produce reasonable flux of X-rays plenty of energy has to be wasted into heat which has to be removed.
The spectral lines generated depends on the target (anode) element used and thus are called characteristic lines. Usually these are transitions from upper shells into K shell (called K lines), into L shell (called L lines) and so on. There is also a continuum Bremsstrahlung radiation given off by the electrons as they are scattered by the strong electric field near the high-Z (proton number) nuclei. The shortest continuum wavelength is determined by the energy of the incident electron, hence by the accelerating voltage on the X-ray tube.
Radiographs obtained using X-rays can be used to identify a wide spectrum of pathologies. Due to their short wavelength, in medical applications, X-rays act more like a particle than a wave. This is in contrast to their application in crystallography, where their wave-like nature is most important.
To generate an image of the cardiovascular system, including the arteries and veins (angiography) an initial image is taken of the anatomical region of interest. A second image is then taken of the same region after iodinated contrast material has been injected into the blood vessels within this area. These two images are then digitally altered, leaving an image of only the iodinated contrast outlining the blood vessels. The doctor (Radiologist) or surgeon then compares the image obtained to normal anatomical images to determine if there is any damage or blockage of the vessel.
To take an X-ray of the bones, short X-ray pulses are shot through a body with radiographic film behind. The bones absorb the most photons by the photoelectric process, because they are more electron-dense. The X-rays that do not get absorbed turn the photographic film from white to black, leaving a white shadow of bones on the film.
For most modern non-medical applications, X-ray production is achieved by synchrotrons (see synchrotron light).
Before computers and before digital imaging, a photographic plate was used to produce radiographic images. The images were produced right on the glass plates. Film replaced these plates and was used in hospitals to produce images. Now computed & digital radiography has started to replace film in medicine, though film technology is still used in industrial radiography processes (e.g. to inspect welded seams). Photographic plates are a thing of history, and their replacement (intensifying screens) is now becoming part of that same history. Silver (necessary to the radiographic & photographic industry) is a non-renewable resource, that has now been replaced by digital (DR) and computed (CR) technology. Where film required wet processing facilities on site, these new technologies do not. Archiving of these new technologies is also space saving for facilities.
Regardless of whether the image receptor technology is plate, film or CR/DR Since photographic plates were sensitive to X-rays, they provide a convenient and easy means of recording the image, but they required a lot of exposure (to the patient). This is where intensifying screens came into the picture. The use of such, allowed for a lower dose to the patient – because the screens took the X-ray information and "intensified" it so that it could be recorded on the film lying next to the intensifying screen.
The part of the patient to be X-rayed is placed between the X-ray source and the image receptor to produce what is a shadow of all the internal structure of that particular part of the body being X-rayed. X-rays are somewhat blocked ("attenuated") by dense tissues such as bone, and pass more easily through soft tissues. Those areas where the X-rays strike the image receptor will produce photographic density (ie. it will turn black when developed). So where the X-rays pass through "soft" parts of the body such as organs, muscle, and skin, the plate or film turns black.
Contrast compounds containing barium or iodine, which are radiopaque, can be ingested in the gastrointestinal tract (barium) or injected in the artery or veins to highlight these vessels. The contrast compounds have high atomic numbered elements in them that (like bone) essentially block the X-rays and hence the once hollow organ or vessel can be more readily seen. In the pursuit of a non-toxic contrast material, many types of high atomic number elements were experimented with. For example, the first time the forefathers used contrast it was chalk, and was used on a cadaver's vessels. Unfortunately, some elements chosen proved to be harmful – for example, many years ago thorium was used as a contrast medium (Thorotrast) – which turned out to be toxic in some cases (causing injury and occasionally death from the effects of thorium poisoning). Contrast material used today has come a long way, and while there is no way to determine who may have a sensitivity to the contrast – the occasions of having an "allergic-type reaction" are very low. (The risk is compared to that associated with penicillin ... that is, just as many people are allergic to penicillin as they are to radiographic contrast material.)
Ultimately, the electrons form a virtual cathode around the anode wire, drastically reducing the electric field in the outer portions of the tube. This halts the collisional ionizations and limits further growth of avalanches. As a result, all "counts" on a Geiger counter are the same size and it can give no indication as to the particle energy of the radiation, unlike the proportional counter. The intensity of the radiation is measurable by the Geiger counter as the counting-rate of the system.
In order to gain energy spectrum information, a diffracting crystal may be used to first separate the different photons. The method is called wavelength dispersive X-ray spectroscopy (WDX or WDS). Position-sensitive detectors are often used in conjunction with dispersive elements. Other detection equipment that is inherently energy-resolving may be used, such as the aforementioned proportional counters. In either case, use of suitable pulse-processing (MCA) equipment allows digital spectra to be created for later analysis.
For many applications, counters are not sealed but are constantly fed with purified gas, thus reducing problems of contamination or gas aging. These are called "flow counters".
X-rays are also used in "real-time" procedures such as angiography or contrast studies of the hollow organs (e.g. barium enema of the small or large intestine) using fluoroscopy acquired using an X-ray image intensifier. Angioplasty, medical interventions of the arterial system, rely heavily on X-ray-sensitive contrast to identify potentially treatable lesions.
Practical application in medical imaging didn't start taking place until the 1990s. Currently amorphous selenium is used in commercial large area flat panel X-ray detectors for mammography and chest radiography. Current research and development is focused around pixel detectors, such as CERN's energy resolving Medipix detector.
Note: A standard semiconductor diode, such as a 1N4007, will produce a small amount of current when placed in an X-ray beam. A test device once used by Medical Imaging Service personnel was a small project box that contained several diodes of this type in series, which could be connected to an oscilloscope as a quick diagnostic.
Silicon drift detectors (SDDs), produced by conventional semiconductor fabrication, now provide a cost-effective and high resolving power radiation measurement. Unlike conventional X-ray detectors, such as Si(Li)s, they do not need to be cooled with liquid nitrogen.
Though X-rays are invisible it is possible to see the ionization of the air molecules if the intensity of the X-ray beam is high enough. The beamline from the wiggler at the ID11 at ESRF is one example of such high intensity
Since Röntgen's discovery that X-rays can identify bony structures, X-rays have been developed for their use in medical imaging. Radiology is a specialized field of medicine. Radiographers employ radiography and other techniques for diagnostic imaging. This is probably the most common use of X-ray technology.
X-rays are especially useful in the detection of pathology of the skeletal system, but are also useful for detecting some disease processes in soft tissue. Some notable examples are the very common chest X-ray, which can be used to identify lung diseases such as pneumonia, lung cancer or pulmonary edema, and the abdominal X-ray, which can detect ileus (blockage of the intestine), free air (from visceral perforations) and free fluid (in ascites). In some cases, the use of X-rays is debatable, such as gallstones (which are rarely radiopaque) or kidney stones (which are often visible, but not always). Also, traditional plain X-rays pose very little use in the imaging of soft tissues such as the brain or muscle. Imaging alternatives for soft tissues are computed axial tomography (CAT or CT scanning), magnetic resonance imaging (MRI) or ultrasound. Since 2005, X-rays are listed as a carcinogen by the U.S. government.
Radiotherapy, a curative medical intervention, now used almost exclusively for cancer, employs higher energies of radiation.
The efficiency of X-ray tubes is less than 2%. Most of the energy is used to heat up the anode.
Other notable uses of X-rays include
Among the important early researchers in X-rays were Professor Ivan Pulyui, Sir William Crookes, Johann Wilhelm Hittorf, Eugen Goldstein, Heinrich Hertz, Philipp Lenard, Hermann von Helmholtz, Nikola Tesla, Thomas Edison, Charles Glover Barkla, Max von Laue, and Wilhelm Conrad Röntgen.
There are conflicting accounts of his discovery because Röntgen had his lab notes burned after his death, but this is a likely reconstruction by his biographers. Röntgen was investigating cathode rays with a fluorescent screen painted with barium platinocyanide and a Crookes tube which he had wrapped in black cardboard so the visible light from the tube wouldn't interfere. He noticed a faint green glow from the screen, about 1 meter away. The invisible rays coming from the tube to make the screen glow were passing through the cardboard. He found they could also pass through books and papers on his desk. Röntgen threw himself into investigating these unknown rays systematically. Two months after his initial discovery, he published his paper.
Röntgen discovered its medical use when he saw a picture of his wife's hand on a photographic plate formed due to X-rays. His wife's hand's photograph was the first ever photograph of a human body part using X-rays.
Physicist Johann Hittorf (1824 – 1914) observed tubes with energy rays extending from a negative electrode. These rays produced a fluorescence when they hit the glass walls of the tubes. In 1876 the effect was named "cathode rays" by Eugen Goldstein, and today are known to be streams of electrons. Later, English physicist William Crookes investigated the effects of electric currents in gases at low pressure, and constructed what is called the Crookes tube. It is a glass cylinder mostly (but not completely) evacuated, containing electrodes for discharges of a high voltage electric current. He found, when he placed unexposed photographic plates near the tube, that some of them were flawed by shadows, though he did not investigate this effect. Crookes also noted that his cathode rays caused the glass walls of his tube to glow a dull blue colour. Crookes failed to realise that it wasn't actually the cathode rays that caused the blue glow, but the low-level X-rays produced when the cathode rays struck the glass.
The first medical X-ray made in the United States was obtained using a discharge tube of Pulyui's design. In January 1896, on reading of Röntgen's discovery, Frank Austin of Dartmouth College tested all of the discharge tubes in the physics laboratory and found that only the Pulyui tube produced X-rays. This was a result of Pulyui's inclusion of an oblique "target" of mica, used for holding samples of fluorescent material, within the tube. On 3 February 1896 Gilman Frost, professor of medicine at the college, and his brother Edwin Frost, professor of physics, exposed the wrist of Eddie McCarthy, whom Edwin had treated some weeks earlier for a fracture, to the x-rays and collected the resulting image of the broken bone on gelatin photographic plates obtained from Howard Langill, a local photographer also interested in Röntgen's work.
X-rays were first generated and detected by Fernando Sanford (1854-1948), the foundation Professor of Physics at Stanford University, in 1891. From 1886 to 1888 he had studied in the Hermann Helmholtz laboratory in Berlin, where he became familiar with the cathode rays generated in vacuum tubes when a voltage was applied across separate electrodes, as previously studied by Heinrich Hertz and Philipp Lenard. His letter of January 6, 1893 (describing his discovery as "electric photography") to The Physical Review was duly published and an article entitled Without Lens or Light, Photographs Taken With Plate and Object in Darkness appeared in the San Francisco Examiner.
Before the 20th century until the 1920s, X-rays were generated in cold cathode tubes, called Crookes tubes. These tubes had to contain a small quantity of gas (invariably air) as a current will not flow in such a tube if they are fully evacuated. One of the problems with early X-ray tubes is that the generated X-rays caused the glass to absorb the gas and consequently the efficiency quickly falls off. Larger and more frequently used tubes were provided with devices for restoring the air, known as 'softeners'. This often took the form of small side tube which contained a small piece of mica – a substance that traps comparatively large quantities of air within its structure. A small electrical heater heats the mica and causes it to release a small amount of air restoring the tube's efficiency. However the mica itself has a limited life and the restore process was consequently difficult to control.
In 1904, John Ambrose Fleming invented the thermionic diode valve (vacuum tube). This used a heated cathode which permitted current to flow in a vacuum. This idea was quickly applied x-ray tubes, and heated cathode x-ray tubes, called Coolidge tubes, replaced the troublesome cold cathode tubes by about 1920.
Two years later, physicist Charles Barkla discovered that X-rays could be scattered by gases, and that each element had a characteristic X-ray. He won the 1917 Nobel Prize in Physics for this discovery. Max von Laue, Paul Knipping and Walter Friedrich observed for the first time the diffraction of X-rays by crystals in 1912. This discovery, along with the early works of Paul Peter Ewald, William Henry Bragg and William Lawrence Bragg gave birth to the field of X-ray crystallography. The Coolidge tube was invented the following year by William D. Coolidge which permitted continuous production of X-rays; this type of tube is still in use today.
The use of X-rays for medical purposes (to develop into the field of radiation therapy) was pioneered by Major John Hall-Edwards in Birmingham, England. In 1908, he had to have his left arm amputated owing to the spread of X-ray dermatitis 
The X-ray microscope was invented in the 1950s.
The Chandra X-ray Observatory, launched on July 23, 1999, has been allowing the exploration of the very violent processes in the universe which produce X-rays. Unlike visible light, which is a relatively stable view of the universe, the X-ray universe is unstable, it features stars being torn apart by black holes, galactic collisions, and novas, neutron stars that build up layers of plasma that then explode into space.
An X-ray laser device was proposed as part of the Reagan administration's Strategic Defense Initiative in the 1980s, but the first and only test of the device (a sort of laser "blaster", or death ray, powered by a thermonuclear explosion) gave inconclusive results. For technical and political reasons, the overall project (including the X-ray laser) was de-funded (though was later revived by the second Bush administration as National Missile Defense using different technologies).