"Quarantine" is the fourth episode of science fiction sitcom Red Dwarf Series V and the twenty eighth in the series run. It was first broadcast on the British television channel BBC2 on 12 March 1992. The episode, fifth to be filmed, was the first one to be solely directed by Rob Grant & Doug Naylor. The episode has Rimmer contracting a holo-virus and turning against the rest of the crew.
There, in Bay 47, nothing gets in and nothing gets out, not even a molecule. The only things the internees have to entertain them are a knitting magazine and a video entitled Wallpapering, Painting and Stippling - a DIY Guide. Predictably, Lister, Kryten and Cat soon start getting on each other's nerves - much to Rimmer's delight.
However, it turns out that Rimmer is the one that has been contaminated with a holo-virus and as a result appears wearing a red and white checked gingham dress and army boots, teams up with a glove puppet named Mr. Flibble and sentences his naughty shipmates to two hours W.O.O (With Out Oxygen). Things look pretty bad, but by using the good luck virus taken from the Viral Research Department, Lister is able to get them out of Quarantine, and his luck holds out as they manage to defeat Rimmer.
The original idea was to have each of the crew infected with Psi-powers, but this was later changed to the positive viruses story. Time constraints, coupled with the fact that it was pitched as the cheap show, meant that the script wasn't developed as well as Grant and Naylor had hoped. It was the cheap show so that the others were affordable.
The character of Dr Hildegarde Lanstrom may be a reference to the molecular biologist Dr Hildegarde Lamfrom.
The episode proved popular enough with the BBC to head one of the two Series V video releases. The BBC had decided to ignore the original running order and used the most popular episodes from Series V to maximise sales of the videos. The episode that featured on the other Series V video release being "Back to Reality".