Proteinase 3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Wipo Publishes Patent of Konkuk University Industrial Cooperation, Shin Chan Young, Kim Soo Hyun, Bae Su Young, Kwon Kyoung Ja for "Uses of a Monoclonal Antibody to Proteinase-3 as a Therapeutic Agent or as a Diagnostic Agent for a Stroke" (South Korean Inventors)
Aug 20, 2012; GENEVA, Aug. 20 -- Publication No. WO/2012/108650 was published on Aug. 16. Title of the invention: "USES OF A MONOCLONAL...