, a propionate-CoA ligase
is an enzyme
the chemical reaction
- ATP + propanoate + CoA AMP + diphosphate + propanoyl-CoA
The 3 substrates of this enzyme are ATP, propanoate, and CoA, whereas its 3 products are AMP, diphosphate, and propanoyl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is propanoate:CoA ligase (AMP-forming). This enzyme is also called propionyl-CoA synthetase. This enzyme participates in propanoate metabolism.
- Ricks CA, Cook RM "Regulation of volatile fatty acid uptake by mitochondrial acyl CoA synthetases of bovine liver". J. Dairy. Sci. 64 2324–35.
- The CAS registry number for this enzyme class is .
Gene Ontology (GO) codes