The Pra River is a river in Ghana. The Pra is the easternmost and the largest of the three principal rivers that drain the area south of the Volta divide. Rising south of the Kwahu Plateau and flowing southward, the Pra enters the Gulf of Guinea east of Takoradi. In the 19th century, the Pra served as the border between the Ashanti Confederacy and the Gold Coast. In the early part of the twentieth century, the Pra was used extensively to float timber to the coast for export. This trade is now carried by road and rail transportation.