Powderkeg fights the Avengers during a failed mass prison escape occurring at the Vault ("Venom Deathrap: The Vault"). During the incident, he follows the leader of the breakout, Venom. Teamed with Mentallo and Vermin, they temporarily defeate Iron Man and Hank Pym. The entire breakout is soon neutralized by technological means pumped through Mentallo.
Powderkeg is later recruited by Doctor Octopus to join his incarnation of the Masters of Evil during the Infinity War. The Masters of Evil confront the Guardians of the Galaxy in the Avengers Mansion. They both become embroiled in a fight against evil doubles of both teams. When Doctor Octopus encourages his team to turn on the Guardians, the Masters, rebel, not wanting to, at that point, harm the people who fought side by side with them. The Masters flee the building, pursuing Octopus.
He's recently appeared in Brand New Day as one of the villains in the bar.