Pleurobema is a genus of freshwater river mussels, aquatic bivalve mollusks in the Unionidae family.

Species within the genus Pleurobema

• highnut (Pleurobema altum)
• hazel pigtoe (Pleurobema avellanum)
• Pleurobema beadleianum
• scioto pigtoe (Pleurobema bournianum)
• painted clubshell (Pleurobema chattanoogaense)
• club naiad (Pleurobema clava)
• James River spinymussel (Pleurobema collina)
• Pleurobema cordatum
• black clubshell (Pleurobema curtum)
• southern clubshell (Pleurobema decisum)
• yellow pigtoe (Pleurobema flavidulum)
• dark pigtoe (Pleurobema furvum)
• southern pigtoe (Pleurobema georgianum)
• Cumberland pigtoe (Pleurobema gibberum)
• brown pigtoe (Pleurobema hagleri)
• Georgia pigtoe (Pleurobema hanleyianum)
• Alabama pigtoe (Pleurobema johannis)
• flat pigtoe (Pleurobema marshalli)
• Coosa pigtoe (Pleurobema murrayense)
• longnut (Pleurobema nucleopsis)
• Tennessee clubshell (Pleurobema oviforme)
• ovate clubshell (Pleurobema perovatum)
• rough pigtoe pearly mussel (Pleurobema plenum)
• oval pigtoe (Pleurobema pyriforme)
• Pleurobema riddellii
• warrior pigtoe (Pleurobema rubellum)
• pyramid pigtoe (Pleurobema rubrum)
• Round Pigtoe, (Pleurobema sintoxia)
• fuzzy pigtoe (Pleurobema strodeanum)
• heavy pigtoe (Pleurobema taitianum)
• Alabama clubshell (Pleurobema troschelianum)
• true pigtoe (Pleurobema verum)