Pixantrone (rINN, codenamed BBR2778) is an immunosuppressant drug, an analogue of mitoxantrone with less toxic effects on cardiac tissue. It is being studied as an antineoplastic for different kinds of cancer, including solid tumors and hematological malignancies such as non-Hodgkin lymphomas.

It is also as potent as mitoxantrone in animal models of multiple sclerosis; however, results of human trials had not been published in 2007.

As of 2007, several phase III clinical trials of pixantrone are underway.


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