This hexahydric alcohol exists as its stereoisomer - myo-inositol.
Upon hydrolysis, they yield 1 mole of glycerol, 2 moles of fatty acid, 1 mole of inositol and 1, 2, or 3 moles of phosphoric acids.
They are regarded to be the most acidic of all the phospholipids.
Hydroxyl group two and six can probably not be phosphoroylated because of steric hindrance.
All seven variations have been found in animals but only six in plant cells (not phosphatidylinositol (3,4,5)-trisphosphate}..
Haloperidol induces the nuclear translocation of phosphatidylinositol 3'-kinase to disrupt Akt phosphorylation in PC12 cells
Sep 01, 2007; Objective: The antipsychotic drug haloperidol (HAL) has been linked to apoptosis and to inhibition of prosurvival Akt signalling...