1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD⁺ $rightleftharpoons$ 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + NADH + H⁺

Thus, the two substrates of this enzyme are 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine and NAD⁺, whereas its 3 products are 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine:NAD+ Delta12-oxidoreductase. Other names in common use include oleate desaturase, linoleate synthase, oleoyl-CoA desaturase, and oleoylphosphatidylcholine desaturase.

References

• Pugh EL, Kates M "Characterization of a membrane-bound phospholipid desaturase system of candida lipolytica". Biochim. Biophys. Acta. 380 442–53.
• Slack CR, Roughan PG, Browse J "Evidence for an oleoyl phosphatidylcholine desaturase in microsomal preparations from cotyledons of safflower (Carthamus tinctorius) seed". Biochem. J. 179 649–56.
• Stymne S, Appelqvist LA "The biosynthesis of linoleate from oleoyl-CoA via oleoyl-phosphatidylcholine in microsomes of developing safflower seeds". Eur. J. Biochem. 90 223–9.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes