He held a high command in the army of Romanus IV Diogenes. After the Battle of Manzikert (1071), he commanded the forces of the fortress Romanopolis. As the only remaining Byzantine general in the southeast he established a quasi-autonomous realm, which stretched from Cilicia to Edessa. The core of his army was composed of 8,000 "Franks" (Normans) under Raimbaud. In 1078, at the beginning of the rule of Nicephorus III Botaniates, he became duke of Antioch, which included Edessa. Several seals testify him as megas domestikos and protokuropalates, then sebastos, then even protosebastos. In December 1084, he lost Antioch to Suleiman I, Sultan of Rum. In 1087, Edessa fell to Malik Shah and Philaretos escaped back to the fortress of Germanicia. However, some sources indicate that he died in 1086. He was the last well-known Scholen Domestikos of Anatolia. His sons handed Germanicia to the First Crusade in 1098.